盐酸利托君治疗前置胎盘的临床疗效观察

Clinical effect of Ritodrine hydrochloride on placenta previa

目的研究盐酸利托君治疗前置胎盘的临床疗效。方法选取30例前置胎盘孕妇,按照随机数字表法分组,每组15例。对照组采用硫酸镁治疗,试验组采用盐酸利托君治疗。比较两组孕妇的治疗效果。结果两组新生儿1 min Apgar评分及新生儿窒息率比较,差异无统计学意义(P>0.05)。试验组新生儿出生1个月、3个月、6个月的身高、体重与对照组比较,差异无统计学意义(P>0.05)。试验组治疗后月经量少于对照组,子宫内膜厚度、子宫内膜容积均大于对照组(P<0.05)。试验组孕妇延长孕周(4.30±1.07)周,对照组孕妇延长孕周(3.33±0.78)周,差异有统计学意义(P<0.05)。试验组治疗总有效率高于对照组(P<0.05)。试验组保胎成功率、妊娠至足月率、12 h、24 h的阴道停止出血率高于对照组(P<0.05)。试验组不良反应发生率低于对照组(P<0.05)。结论前置胎盘孕妇采用盐酸利托君治疗,可提升临床疗效,改善新生儿分娩结局,提升治疗效果,值得临床推广。

Objective To study the clinical effect of Ritodrine hydrochloride on placenta previa.Methods A total of 30 pregnant women with placenta previa were selected and divided into 15 cases in each group according to random number table method.The control group was treated with magnesium sulfate and the experimental group was treated with Ritodrine hydrochloride.The therapeutic effect of the two groups of pregnant women was compared.Results There was no significant difference in Apgar score and neonatal asphyxia rate within 1 min between the two groups(P>0.05).There was no significant difference between the experimental group and the control group in height and weight at 1 month,3 months and 6 months(P>0.05).After treatment,the menstrual volume of experimental group was lower than that of control group,and the endometrial thickness and endometrial volume were higher than that of control group(P<0.05).Pregnant women in the experimental group extended their gestation weeks(4.30±1.07)weeks,while those in the control group extended their gestation weeks(3.33±0.78)weeks,and the difference was statistically significant(P<0.05).The total effective rate of experimental group was higher than that of control group(P<0.05).The success rate of fetal protection,pregnancy to term rate,12 h and 24 h vaginal stopping bleeding rate of experimental group were higher than those of control group(P<0.05).The incidence of adverse reactions in experimental group was lower than that in control group(P<0.05).Conclusion The treatment of placenta previa pregnant women with ritodrine hydrochloride can improve the clinical efficacy,improve the outcome of neonatal delivery,improve the therapeutic effect,worthy of clinical promotion.