唾液腺超声在干燥综合征的应用进展

Advances in the Application of Salivary Gland Ultrasound in Sjogren Syndrome

干燥综合征是以侵犯泪腺和唾液腺为主的慢性淋巴细胞高度浸润的自身免疫性疾病,在风湿免疫领域,干燥综合征发病率仅次于类风湿性关节炎。临床除有涎腺和泪腺功能下降而出现口干、眼干症状外,尚有其他外分泌腺及腺体外其他器官受累而出现多系统损害的症状。目前诊断干燥综合征的标准中,涎腺造影和唇腺活检均为有创检查,具有局限性,部分患者无法接受,且这些方法可能导致假阳性结果。唾液腺超声是一种廉价、易获得、无辐射、可重复的检查方法,广泛应用于干燥综合征检查中,具有较高的准确度。本文对唾液腺超声在干燥综合征中的进展、超声表现及临床意义进行综述。

Sjogren syndrome is an autoimmune disease with high infiltration of chronic lymphocytes mainly invading the lacrimal and salivary glands,and in the field of rheumatic immunity,the incidence of sjogren syndrome is second only to rheumatoid arthritis.In addition to symptoms of dry mouth and dry eyes due to decreased function of salivary glands and lacrimal glands,clinical symptoms of multi-system damage due to involvement of other exocrine glands and other organs outside the glands are also present.Among the current criteria for diagnosing sjogren syndrome,salivary gland imaging and lacrimal gland biopsy are invasive tests with limitations that are unacceptable to some patients,and these methods may lead to false-positive results.Salivary gland ultrasound is an inexpensive,easily accessible,radiation-free and reproducible examination method,which is widely used in the examination of sjogren syndrome and has a high accuracy.This paper reviews the progress,ultrasound performance and clinical significance of salivary gland ultrasound in sjogren syndrome.