危重病人谵妄非药物预防策略的证据总结

Summary of the best evidence for non-pharmacological interventions on delirium prevention in critically ill patients

目的:检索、评价和总结危重症病人谵妄非药物预防策略的最佳证据。方法:针对危重症病人谵妄非药物预防策略提出问题,根据6S证据模型检索文献,检索时限为2010年1月—2022年2月,由2名研究者对检索到的文献进行质量评价及证据汇总。结果:最终纳入21篇文献,其中证据总结3篇,指南8篇,专家共识1篇,系统评价9篇,汇总出54条危重症病人谵妄非药物预防策略的最佳证据,包括谵妄的培训、评估与筛查、防治策略和随访。结论:基于现有指南及系统评价总结的危重病人谵妄非药物预防策略的最佳证据,可为临床实践提供循证依据。

Objective:To search,evaluate,and summarize the best evidence for non-pharmacological prevention strategies for delirium in critically ill patients.Methods:To address the issue of non-pharmacological prevention strategies for delirium in critically ill patients,literature was retrieved using the 6S evidence model from January 2010 to February 2022.Two researchers evaluated the quality of the retrieved literature and summarized the evidence.Results:21 articles were ultimately included,including 3 evidence summaries,8 guidelines,1 expert consensus,and 9 systematic evaluations.54 pieces of best evidence for non-drug prevention strategies for delirium in critically ill patients were summarized,including delirium training,evaluation and screening,prevention and treatment strategies,and follow-up.Conclusion:This study summarizes the best evidence for non-pharmacological prevention strategies for delirium in critically ill patients,which can provide evidence-based evidence for clinical practice.