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2257例孕产妇B族链球菌感染情况及其对母婴结局的影响

Group B Streptococcus infection in 2257 pregnant women and its influence on maternal and infant outcomes
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摘要 目的探讨常州地区孕产妇B族链球菌(GBS)感染情况及其对母婴结局的影响。方法选取2021年7月至2022年7月在常州市妇幼保健院进行产检并分娩的2257例孕产妇作为研究对象。孕产妇均进行GBS检测,比较不同年龄段孕产妇GBS感染情况及其不良妊娠结局、新生儿不良结局发生情况。结果2257例中,GBS阳性(观察组)80例,阳性率为3.5%;GBS阴性2177例(对照组);其中≥35岁GBS阳性率最高,21~30岁GBS阳性率最低。观察组的不良妊娠结局发生率、新生儿不良结局发生率高于对照组(P<0.05)。结论孕产妇GBS感染会增加不良母婴结局发生率,临床应对孕产妇GBS感染情况进行积极监测。 Objective To investigate Group B Streptococcus(GBS)infection in pregnant women in Changzhou and its influence on maternal and infant outcomes.Methods A total of 2257 pregnant women who underwent prenatal examination and delivered in Changzhou Maternal and Child Health Care Hospital from July 2021 to July 2022 were selected as the research objects.Pregnant women were tested for GBS,and the incidence of GBS infection,adverse pregnancy outcomes and adverse neonatal outcomes in different age groups were compared.Results Among the 2257 cases,80 cases were GBS positive(the observation group),the positive rate was 3.5%,2177 cases were GBS negative(the control group).The GBS positive rate was highest in≥35 years old group and lowest in 21-30 years old group.The incidence of adverse pregnancy outcomes and adverse neonatal outcomes in the observation group was higher than that in the control group(P<0.05).Conclusion Pregnant women with GBS infection can increase the incidence of adverse maternal and infant outcomes,and GBS infection in pregnant wom en should be actively monitored.
作者 王微 王晶 陈文仪 张玢 WANG Wei;WANG Jing;CHEN Wenyi;ZHANG Bin(Department of Medicine Genetics,Changzhou Maternal and Child Health Care Hospital,Jiangsu Province,Changzhou 213000,China)
出处 《妇儿健康导刊》 2023年第11期74-76,83,共4页 JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
基金 常州市“十四五”卫生健康高层次人才培养工程(2022CZBJ089)。
关键词 妊娠晚期 B族链球菌 不良妊娠结局 新生儿不良结局 荧光定量PCR Late pregnancy Group B Streptococcus Adverse pregnancy outcome Adverse neonatal outcome Fluorescence quantitative PCR
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