小儿双金清热口服液联合奥司他韦治疗甲型流行性感冒患儿的临床效果

Clinical effect of Xiao’er Shuangjin Qingre Oral Liquid combined with Oseltamivir in the treatment of children with influenza A

目的探讨小儿双金清热口服液联合奥司他韦治疗甲型流行性感冒患儿的临床效果。方法选取2018年8月至2019年8月泰安市中心医院分院收治的120例甲型流行性感冒患儿作为研究对象,按照随机数字表法分为参照组(n=60)和研究组(n=60)。参照组采用奥司他韦治疗,研究组采用小儿双金清热口服液联合奥司他韦治疗。比较两组临床疗效、临床症状消失时间、免疫水平及不良反应发生情况。结果研究组总有效率高于参照组(P<0.05)。研究组临床症状消失时间均短于参照组(P<0.05)。治疗后,研究组免疫球蛋白A、免疫球蛋白M及免疫球蛋白G水平均高于参照组(P<0.05)。研究组不良反应总发生率低于参照组(P<0.05)。结论小儿双金清热口服液联合奥司他韦治疗甲型流行性感冒患儿,可有效改善临床症状,提高患儿免疫水平,且不良反应发生风险较低。

Objective To investigate the clinical effect of Xiao’er Shuangjin Qingre Oral Liquid combined with Oseltamivir in the treatment of children with influenza A.Methods A total of 120 children with influenza A admitted to Branch of Tai’an City Central Hospital from August 2018 to August 2019 were selected as the research objects and divided into the control group(n=60)and the study group(n=60)according to the random number table method.The control group was treated with Oseltamivir,and the study group was treated with Xiao’er Shuangjin Qingre Oral Liquid combined with Oseltamivir.The clinical efficacy,duration of symptom disappearance,immune levels and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group(P<0.05).The disappearance time of clinical symptoms in the study group was shorter than that in the control group(P<0.05).After treatment,the levels of immunoglobulin A,immunoglobulin M and immunoglobulin G in the study group were higher than those in the control group(P<0.05).The total incidence of adverse reactions in the study group was lower than that in the control group(P<0.05).Conclusion Xiao’er Shuangjin Qingre Oral Liquid combined with Oseltamivir in the treatment of children with influenza A,can effectively improve clinical symptoms and the immune levels of children wit h low risk of adverse reactions.