氮掺杂碳量子点@花状氧化锌检测L-色氨酸

Detection of L-tryptophan by nitrogen doped carbon quantum dots@flower shaped zinc oxide

通过水热法制备N-CQDs@ZnO复合材料,使用傅里叶变换红外光谱、X射线衍射仪、荧光光谱、紫外-可见光吸收光谱、透射电镜对复合材料进行表征.然后,将复合材料修饰在玻碳电极上,构筑一种用于检测L-色氨酸的新型电化学传感平台,采用循环伏安法(CV)、差分脉冲伏安法(DPV)、电化学阻抗法(EIS)进行电化学研究.在优化条件下,N-CQDs@ZnO4/GCE对于L-色氨酸的检出限为32 nmol·L-1,灵敏度为0.78μAμmol·L-1cm-2,该传感器成功应用于血清中L-色氨酸的检测.

In this work,N-CQDs@ZnO composites were prepared by hydrothermal method,and characterized by Fourier transform infrared spectroscopy,X-ray diffractometer,fluorescence spectrum,UV-visible absorption spectrum and transmission electron microscopy.Then,a novel electrochemical sensing platform for L-tryptophan detection was constructed by modifying the composite material on the GCE.Cyclic voltammetry(CV)、differential pulse voltammetry(DPV)and electrochemical impedance(EIS)were used for electrochemical research.Under optimized conditions,the detection limit of N-CQDs@ZnO4/GCE for L-tryptophan was 32 nmol·L-1,and the sensitivity was 0.78μAμmol·L-1cm-2.The sensor was successfully applied to the detection of L-tryptophan in serum.