克龄蒙联合坤泰胶囊治疗卵巢早衰对患者血清性激素水平的影响观察

Effect of kelingmeng combined with kuntai capsule on serum sex hormone levels in patients with premature ovarianEffect of kelingmcng combined with kuntai capsule on serum sex hormone levels in patients with premature ovarian failure

目的探究克龄蒙联合坤泰胶囊治疗卵巢早衰对患者血清性激素水平的影响。方法选取96例卵巢早衰患者,按照随机数字表法分为对照组与研究组,每组48例。对照组接受克龄蒙治疗,研究组在对照组基础上接受坤泰胶囊治疗。比较两组临床疗效、血清性激素水平及不良反应发生率。结果研究组临床治疗总有效率97.92%高于对照组的81.25%(P<0.05)。研究组不良反应发生率略高于对照组,但差异无统计学意义(P>0.05)。治疗前,两组促黄体生成素(LH)、雌激素(E_(2))、卵泡刺激素(FSH)水平比较,差异无统计学意义(P>0.05);研究组治疗后LH、FSH水平低于对照组,E_(2)水平高于对照组(P<0.05)。结论对卵巢早衰患者实施克龄蒙联合坤泰胶囊治疗可以有效改善性激素水平,提高治疗效果,且治疗安全性有保障。

Objective To explore the effect of Kelingmeng combined with Kuntai capsule on serum sex hormone levels in patients with premature ovarian failure.Methods 96 patients with premature ovarian failure were selected and divided into control group and study group according to random number table method,with 48 cases in each group.The control group was treated with Kelingmeng,and the study group was treated with Kuntai capsule on the basis of the control group.The clinical efficacy,serum sex hormone levels and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of the study group was 97.92%higher than that of the control group(81.25%,P<0.05).The incidence of ADR in the study group was slightly higher than that in the control group,but the difference was not statistically significant(P>0.05).Before treatment,there was no significant difference in the levels of luteinizing hormone(LH),estrogen(E_(2))and follicle stimulating hormone(FSH)between 2 groups(P>0.05).After treatment,LH and FSH levels in the study group were lower than those in the control group,and E_(2) levels were higher than those in the control group(P<0.05).Conclusion The treatment of Kelingmeng combined with Kuntai capsule in patients with premature ovarian failure can effectively improve the level of sex hormones,improve the therapeutic effect,and the safety of treatment is guaranteed.