亚硫酸氢钠催化合成柠檬酸三甲酯

Sodium Bisulfite Catalytic Synthesis of Trimethyl Citrate

以甲醇、柠檬酸为反应原料合成柠檬酸三甲酯,催化剂采用亚硫酸氢钠。考察了反应时间、脱水剂用量、酸醇比等因素对产品收率的影响,最终确定了最佳的合成工艺条件:反应时间5 h,脱水剂用量1.1 g,酸醇物质的量比1∶12,催化剂用量4.0 g,搅拌速度45 r/min,并分析了造成产品收率低的影响因素。

Use methanol,citric acid as raw material,under the catalysis of sodium bisulfite to synthesis trimethyl citrate.Through single-factor experiments,investigated the factors influencing on the yield of the product,and finally got the best synthetic process conditions:the reaction time is 5 h,dehydrating agent dosage is 1.1 g,acid glycol ratio is 1∶12,catalyst dosage is 4.0 g,stirring speed is 45 r/min,and analyzed the influence factors of the low product yield.