循证干预在白血病化疗患者中的应用效果

Application effect of evidence-based intervention in leukemia patients undergoing chemotherapy

目的探讨循证干预在白血病化疗患者中的应用效果。方法根据干预方式的不同将110例白血病化疗患者分为对照组(n=54)和观察组(n=56),对照组患者进行常规干预,观察组患者在对照组的基础上进行循证干预。比较两组患者化疗期间感染率、心理状态[抑郁自评量表(SDS)和焦虑自评量表(SAS)]、睡眠质量[匹兹堡睡眠质量指数(PSQI)]、生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]及满意度。结果观察组患者化疗期间总感染率明显低于对照组(P﹤0.01)。干预后,两组患者SDS、SAS、PSQI评分均低于本组干预前,观察组患者SDS、SAS、PSQI评分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者躯体功能、情绪功能、社会功能、认知功能、角色功能评分均高于本组干预前,观察组患者躯体功能、情绪功能、社会功能、认知功能、角色功能评分均高于对照组,差异均有统计学意义(P﹤0.05)。观察组患者的总满意度明显高于对照组(P﹤0.01)。结论循证干预可降低白血病化疗患者的感染率,改善患者的心理状态和睡眠质量,提高患者的生活质量和满意度。

Objective To investigate the application effect of evidence-based intervention in leukemia patients undergoing chemotherapy.Method A total of 110 leukemia patients undergoing chemotherapy were divided into control group(n=54)and observation group(n=56)according to different intervention methods.Patients in the control group received conventional intervention,and patients in the observation group received evidence-based intervention on the basis of the control group.The infection rate during chemotherapy,psychological state[self-rating depression scale(SDS)and self-rating anxiety scale(SAS)],sleep quality[Pittsburgh sleep quality index(PSQI)],quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ-C30)]and satisfaction were compared between the two groups.Result The total infection rate during chemotherapy in the observation group was significantly lower than that in the control group(P<0.01).After the intervention,the SDS,SAS,and PSQI scores of the two groups were lower than those before the intervention,and the above scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).After the intervention,the physical function,emotional function,social function,cognitive function,and role function scores of the two groups were higher than those before the intervention,and the foregoing scores of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).The total satisfaction rate in the observation group was significantly higher than that in the control group(P<0.01).Conclusion Evidence-based intervention could reduce the infection rate in leukemia patients undergoing chemotherapy,and improve the patients’psychological state,quality of sleep and life,and satisfaction.