摘要
青少年2型糖尿病(type 2 diabetes mellitus,T2DM)在世界范围内的发病率呈上升趋势,与成人相比,青少年T2DM进展更快,二甲双胍治疗的无效率更高,β细胞减少的速度更快。与成人T2DM甚至是1型糖尿病相比,青少年T2DM的并发症发生率和总病死率更高,需要提高对青少年T2DM风险、预防和治疗地了解。因此,本文对国外关于糖尿病基因相关的研究进展以综述方式进行探讨。
The incidence rate of type 2 diabetes(T2DM)in adolescents around the world is on the rise.Compared with adults,T2DM in adolescents is progressing faster,the ineffectiveness rate of metformin treatment is higher,and the rate ofβcell reduction is faster.Compared with adult T2DM and even type 1 diabetes,adolescent T2DM has a higher incidence of complications and mortality.It is necessary to improve the understanding of the risk,prevention and treatment of adolescent T2DM.Therefore,this article reviews the research progress of diabetes gene in foreign countries.
作者
周瑞雯
郭华
任忠英
ZHOU Ruiwen;GUO Hua;REN Zhongying(General Department,Community Health Service Center,Sijing Town,Songjiang District,Shanghai,201600 China;Department of Internal Medicine,Shanghai Ruijin Rehabilitation Hospital,Shanghai,200023 China)
出处
《糖尿病新世界》
2023年第7期194-198,共5页
Diabetes New World Magazine
