基于“肺与大肠相表里理论”的中医方法治疗儿童支原体肺炎的临床效果评价

Evaluation of the Clinical Effect of Traditional Chinese Medicine Treatment of Mycoplasma Pneumonia in Children Based on"the Theory of the Lung and the Large Intestine"

目的探究与分析基于“肺与大肠相表里理论”的中医方法治疗儿童支原体肺炎的临床效果评价。方法采取随机数表法将2020年1月—2022年5月聊城市中医医院收治的120例儿童支原体肺炎患儿分为对照组与观察组,各60例,对照组给予常规西药阿奇霉素治疗,观察组在对照组基础上加用鱼金注射液+复方丹参注射液+生大黄治疗,两组均连续治疗1个月。对比两组疗效、主要症状积分、肺功能及免疫功能指标,同时观察不良反应发生率。结果观察组的临床总有效率明显高于对照组(P<0.05);治疗后观察组与对照组相比,发热、咳嗽、痰壅及喘促评分均较低,最大呼气中段流量(MMEF)、50%肺活量最大呼气流量(MEF50)及25%肺活量最大呼气流量(MEF25)水平均更高,免疫球蛋白A(IgA)升高,免疫球蛋白G(IgG)、免疫球蛋白M(IgM)及免疫球蛋白E(IgE)均降低,差异有统计学意义(P<0.05)。两组患儿在治疗期间均未发现明显的不良反应。结论基于“肺与大肠相表里理论”治疗儿童支原体肺炎可明显促进患儿临床症状及体征的缓解,改善肺功能,提高机体免疫功能,且治疗期间无明显不良反应,安全性较高。

Objective To explore and analyze the clinical effect evaluation of the treatment of mycoplasma pneumonia in children with traditional Chinese medicine based on"the theory of the lung and the large intestine".Methods 120 children with mycoplasma pneumonia treated from January 2020 to May 2022 were divided into control group and observation group,60 cases in each group.The control group was treated with conventional azithromycin,and the observation group was treated with Yujin injection+compound Danshen injection+raw rhubarb on the basis of the control group.Both groups were treated for one month.The efficacy,main symptom scores,lung function and immune function indexes of the two groups were compared,and the incidence of adverse reactions was observed.Results The total clinical effective rate of observation group was significantly higher than that of control group(P<0.05).The scores of fever,cough,phlegm obstructing and wheezing were lower in the observation group than in the control group.The levels of maximum mid-expiratory flow(MMEF),50%maximum expiratory flow(MEF50)and 25%maximum expiratory flow(MEF25)were higher in the observation group after treatment,and immunoglobulin A(IgA)were increased.Immunoglobulin G(IgG),immunoglobulin M(IgM)and immunoglobulin E(IgE)were decreased,and the differences were statistically significant(P<0.05).No obvious adverse reactions were found in both groups during treatment.Conclusion The treatment of mycoplasma pneumonia in children based on the"theory of the surface and the inside of the lung and the large intestine"can significantly promote the relief of clinical symptoms and signs of mycoplasma pneumonia in children,improve lung function,improve the body's immune function,and no obvious adverse reactions during the treatment,with high safety.