期刊文献+

甘油连续生物歧化过程的参数辨识与非线性分析

Parameter identification and nonlinear analysis of the continuous bio-dissimilation process of glycerol
下载PDF
导出
摘要 为了给出能够较好描述甘油连续生物歧化为1,3-丙二醇过程的数学模型以及模型的非线性特性,研究了其参数辨识与非线性分析问题.首先,建立了甘油连续歧化过程的GMA-系统,给出了以模型的计算值与实验测量值误差最小为优化目标、以甘油连续发酵过程的稳态条件为约束的参数辨识优化问题.采用序列二次规划算法,获得了相应动力学系统的最优参数值.结果表明,构建的GMA-系统的参数辨识优化模型能够得到更准确的参数值.其次,将辨识出的参数结果代入到甘油连续歧化过程的GMA-系统中,进行了平衡点计算与稳定性分析等.采用符号化实根隔离法求解了系统的平衡点,依据几乎线性系统的稳定性理论研究了平衡点的稳定性. In order to give a mathematical model that can better describe the continuous bio-dissimilation process of glycerol to 1,3-propanediol and the nonlinear characteristics of the model,the problems of parameter identification and nonlinear analysis are studied.Firstly,the GMA-system for the continuous bio-dissimilation process of glycerol is established.A parameter identification optimization problem is given,which takes the minimum error between the calculated value of the model and the experimental measurement value as the optimization objective and the steady-state conditions of continuous fermentation process of glycerol as constraints.By using the sequential quadratic programming algorithm,the optimal parameter values of the corresponding dynamic system are obtained.The results show that the parameter identification optimization model of the GMA-system can provide more accurate parameter values.Secondly,by substituting the results of the identified parameters into the GMA-system of continuous bio-dissimilation process of glycerol,the equilibrium point calculation and stability analysis are carried out.The equilibrium points of the system are numerically calculated by the method of the symbolic real root isolation,the stability of the equilibrium point is studied according to the stability theory of almost linear system.
作者 张菁朔 徐恭贤 ZHANG Jingshuo;XU Gongxian(College of Mathematical Sciences,Bohai University,Jinzhou 121013,China)
出处 《河北大学学报(自然科学版)》 CAS 北大核心 2023年第3期230-236,共7页 Journal of Hebei University(Natural Science Edition)
基金 国家自然科学基金资助项目(11101051) 辽宁省自然科学基金资助项目(20180550839) 辽宁省教育厅科学研究项目(LJ2020015)。
关键词 GMA-系统 参数辨识 平衡点 稳定性 GMA-system parameter identification equilibrium point stability
  • 相关文献

参考文献4

二级参考文献39

  • 1程可可,林日辉,刘宏娟,刘德华.1,3-丙二醇分批发酵动力学模型[J].过程工程学报,2005,5(4):425-429. 被引量:10
  • 2高彩霞,王宗涛,冯恩民,修志龙.微生物间歇发酵生产1,3-丙二醇过程辨识与优化[J].大连理工大学学报,2006,46(5):771-774. 被引量:13
  • 3王育全,沈佐锐,高灵旺,马晓光.一类具有年龄结构的麦蚜-瓢虫模型的全局分析[J].生物数学学报,2007,22(1):59-66. 被引量:2
  • 4Sun Y Q, Qi Wen-Tao, Teng Hu, et al. Mathematical modeling of glycerol fementation by Klebsiella pneumoniae: Concerning enzyme-catalytic reductive pathway and transport of glycerol and 1,3-propanediol across cell membrane[J]. Biochemical Engineering Journal, 2008, 38(1):22-32.
  • 5Feng En-min, Liu Chong-yang, Gong Zhao-hua. Identification of intracellular Kinetic parameters in con- tinuous bioconversion of glycerol by Klebsiella pneumoniae. The Second International Symposium on Optimization and Systems Biology (OSB'08) . Lijiang, China, October 31- November 3, 2008, ORSC & APORC,101-108.
  • 6Wei Niu, Dongming Wang. Algebraic approaches to stability analysis of biological systems[J]. Mathematics in Computer Science, 2008, 1(3):507-539.
  • 7Hao J, Wang W, Tian J S, et al. Decrease of 3-hydroxypropionaldehyde accumulation in 1,3-propanediol production by over-expressing dhaT gene in Klebsiella pneumoniae[J]. Industrial Microbiology g: Biotechnology, 2008, 35(7):735-741.
  • 8Zeng A P, ROSE A, Biebl H, et al. Multiple product inhibition and growth modeling of Clostridium butyricum and Klebsiella pneumoniae in fermentation[J]. Biotechnology and Bioengineering, 1994, 44(8):902- 911.
  • 9Zeng A P,Biotechnology Bioengineering,1996年,52卷,561页
  • 10Zeng A P,Biotech Prog,1995年,11卷,71页

共引文献18

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部