宫颈炎性肌纤维母细胞瘤一例并文献复习

Cervical Inflammatory Myofibroblastic Tumor:A Case Report and Literature Review

宫颈炎性肌纤维母细胞瘤(inflammatory myofibroblastic tumor,IMT)是一种具有中度恶性潜能的间叶性肿瘤,病因不明,临床罕见,临床表现缺乏特异性,确诊依赖于病理学形态及免疫组织化学结果。报告1例宫颈IMT患者情况并复习相关文献,以期提高对该肿瘤的认识。该患者因发现子宫肌瘤5年,阴道不规则出血半个月余收入院,术前行分段性诊刮术+宫颈活检术明确诊断为宫颈IMT,行子宫全切术+双侧附件切除术+双侧卵巢动静脉高位结扎术,术后病理检查证实了术前诊断。实验室检查及影像学检查对宫颈IMT均无特异性,因其与恶性肿瘤相似且不易鉴别,易误诊、漏诊,手术切除为有效治疗方法,建议完整切除病灶,并行子宫全切术,术后需定期随访。

Cervical inflammatory myofibroblastic tumor(IMT)is a type of mesenchymal tumor with moderate malignant potential,unknown etiology,rare clinical manifestations,lack of specificity,its diagnosis depends on pathological morphology and immunohistochemical findings.One patient with cervical IMT was reported and the literature was reviewed to improve understanding of this tumor.The patient was admitted to the hospital due to the discovery of uterine fibroids for 5 years and irregular vaginal bleeding for more than half a month,and was clearly diagnosed as cervical IMT by segmented curettage+cervical biopsy before surgery,complete hysterectomy+bilateral adnexectomy+bilateral ovarian arteriovenous high ligation,and postoperative pathological examination confirmed the preoperative diagnosis.Laboratory tests and imaging examinations are not specific for cervical IMT,because it is similar to malignant tumors and not easy to identify,easily to misdiagnose and missed diagnosis,surgical resection is an effective treatment,it is recommended to completely resect the lesion,and complete hysterectomy,and regular follow-up after surgery.