家庭血压测量、诊室血压测量与动脉粥样硬化间的相关性

Correlation Between Home Blood Pressure Monitoring,Office Blood Pressure Monitoring and Atherosclerosis

目的研究家庭血压测量、诊室血压测量与动脉粥样硬化间的相关性。方法选择2021年6月-10月就诊于安徽医科大学第二附属医院心内科、临床诊断为冠状动脉粥样硬化性心脏病的患者247例,均行冠状动脉造影检查、计算syntax评分,并完善外周四肢血管动脉硬化检查、记录踝臂指数(ABI)、臂踝脉搏波传导速度(baPWV),记录家庭血压测量、诊室血压测量,记录其他临床资料,比较家庭血压测量与诊室血压测量的差异,分析家庭血压测量、诊室血压测量与syntax评分、ABI、baPWV间的相关性,比较家庭血压测量和诊室血压测量与动脉粥样间相关性的大小。结果家庭收缩压(SBP)和诊室SBP比较,差异有统计学意义(P<0.05),家庭舒张压(DBP)和诊室DBP比较,差异无统计学意义(P>0.05);家庭SBP与syntax评分、ABI、baPWV强相关(r=0.779、0.710、0.731,P<0.05),家庭DBP与syntax评分、ABI、baPWV弱相关(r=0.170、0.240、0.238,P<0.05),诊室SBP与syntax评分、ABI、baPWV弱相关(r=0.191、0.218、0.188,P<0.05),诊室DBP与syntax评分、ABI、baPWV弱相关(r=0.187、0.189、0.238,P<0.05);家庭SBP与syntax评分、ABI、baPWV间的相关性大于家庭DBP、诊室SBP、诊室DBP与syntax评分、ABI、baPWV的相关性。结论家庭SBP与冠状动脉和外周动脉硬化的相关性更高,是血管动脉粥样硬化的独立风险预测因子。

Objective To study the correlation between home blood pressure monitoring,office blood pressure monitoring and atherosclerosis.Methods From June to October 2021,247 patients with coronary atherosclerotic heart disease were selected from the Department of Cardiology,the Second Affiliated Hospital of Anhui Medical University.Coronary angiography was performed and syntax score was calculated.Peripheral limb vascular arteriosclerosis examination was performed.Ankle brachial index(ABI)and brachial ankle pulse wave velocity(baPWV)were recorded.Home blood pressure monitoring and office blood pressure monitoring were recorded.Other clinical data were recorded.The differences between home blood pressure measurement and office blood pressure measurement were compared.The correlation between home blood pressure measurement,office blood pressure measurement and syntax score,ABI,baPWV were analyzed,and the correlation between home blood pressure measurement,office blood pressure measurement and atherosclerosis were compared.Results There were statistically significant differences between home SBP and office SBP(P<0.05),and there was no significant difference between home DBP and office DBP(P>0.05);home SBP was strongly correlated with syntax score,ABI and baPWV(r=0.779,0.710,0.731,P<0.05);home DBP was weakly correlated with syntax score,ABI and baPWV(r=0.170,0.240,0.238,P<0.05);office SBP was weakly correlated with syntax score,ABI and baPWV(r=0.191,0.218,0.188,P<0.05);office DBP was weakly correlated with syntax score,ABI and baPWV(r=0.187,0.189,0.238,P<0.05).The association between home SBP and syntax score,ABI and baPWV was much greater than that between home DBP,office SBP and office DBP and syntax score,ABI and baPWV respectively.Conclusion Home SBP is more associated with coronary and peripheral atherosclerosis and is an independent risk predictor of vascular atherosclerosis.