摘要
Background:Postoperative ileus is a major complication of patients undergoing abdominal surgery.The purpose of this study was to determine the effects of operative time and the method of surgery on postoperative ileus.Methods:After institutional review board approval,121 patients were studied in two groups.Group 1 consisted of 86 patients with colorectal cancers and Group 2 included 35 patients with diverticulitis.Various surgical procedures were performed in both groups.In all patients,the nasogastric(NG)tube was removed after termination of surgery.Clear liquids were offered commencing on the first postoperative day,followed by a regular diet as tolerated.GI-1 was the postoperative time to toleration of clear liquids,whereas GI-2 was the postoperative time to first bowel movement or flatus and toleration of a regular diet.Statistical analysis was performed using a linear regression model by disease with the first bowel movement or flatus as the dependent variable and operative time and category as explanatory variables.Results:Vomiting after oral feeding occurred in 18(20.9%)patients with cancer and in 7(20.0%)patients with diverticular disease.An NG tube was reinserted in 13(15.1%)patients in the cancer group and in 3(8.6%)patients in the diverticular disease group.In patients with cancer,the duration of operation was associated with GI-2(P=0.011),whereas in patients with diverticulitis,the duration of operation was associated with GI-1(P=0.001)and GI-2(P=0.044).In the diverticulitis group,a significant relationship was found between GI-2 and operative category(P=0.03).Conclusion:Longer operations led to more prolonged postoperative ileus after both laparoscopy and laparotomy,regardless of malignant or benign pathology.In anticipation of and/or following longer operations,surgeons should consider measures to shorten postoperative ileus.
基金
The authors thank Paula Strassmann and Maristela Percivale for their assistance with the study design and statistical evaluation.
