摘要
肾癌是泌尿生殖系统第三常发的恶性肿瘤,在疾病进展过程中可发生局部和(或)远处转移,严重影响患者预后。随着靶向和免疫治疗在晚期肾癌领域的研究进展,局部进展期肾癌的治疗方案也逐渐发生改变,越来越多的研究开始关注靶向治疗或免疫治疗在其围手术期的应用。本文旨在梳理和综述局部进展期肾癌的研究进展,为制定新的治疗方案提供参考。
Renal cell carcinoma(RCC)is the third most common malignant tumor of the genitourinary system.During disease progression,RCC can undergo local and/or distant metastasis,which seriously affects the prognosis of the patient.With the advancements in targeted therapy and immunotherapy for advanced RCC,treatment for locally advanced RCC has changed.Studies have focused on applying targeted therapy or immunotherapy in the perioperative period.This article aims to review progress on treatment of locally advanced RCC to offer references for novel treatment strategies.
作者
宿佳琦
张海梁
SU Jiaqi;ZHANG Hailiang(Department of Urology,Fudan University Shanghai Cancer Center,Department of Oncology,Shanghai Medical College,Fudan University,Shanghai 200032,China)
出处
《肿瘤防治研究》
CAS
2023年第6期556-561,共6页
Cancer Research on Prevention and Treatment
关键词
局部进展期肾癌
新辅助治疗
手术治疗
辅助治疗
临床试验
Locally advanced renal cell carcinoma
Neoadjuvant therapy
Surgical treatment
Adjuvant therapy
Clinical trial
