胰腺癌腹腔转移诊断方式的研究进展

Diagnosis of abdominal metastasis of pancreatic cancer:research progress

转移发生较早是胰腺癌预后差的重要因素之一。及早发现腹腔转移能够促使患者尽早接受新辅助治疗和转化治疗,避免了非必要的手术创伤。本文综述了影像学方法、实验室方法及联合多方式综合评估等手段对胰腺癌腹腔转移的诊断效能,简述了CT、MRI、超声、肿瘤标志物及miRNA检测等方式在胰腺癌腹腔转移中的应用,并总结了部分采用多类指标综合评判从而提高转移风险预测能力的相关研究成果,以期为临床诊断方式的选择和应用提供借鉴。

Early metastasis is one of the important factors for poor prognosis of pancreatic cancer.Early detection of abdominal metastasis can urge patients to undergo neoadjuvant therapy and conversion therapy as soon as possible and avoid unnecessary surgical trauma.This paper reviews the diagnostic efficacy of imaging methods,laboratory methods and combined multi-mode comprehensive evaluation in patients with abdominal metastasis of pancreatic cancer,briefly describing the application of computed tomography,magnetic resonance imaging,ultrasound,tumor markers,microRNA and other methods,and summarizing the use of multi-index comprehensive evaluation to improve the ability of metastasis risk prediction,so as to provide reference for the selection and application of clinical diagnostic methods.