骨疏汤联合西药治疗老年骨质疏松性胸腰椎压缩性骨折行后路经皮椎体成形术患者的临床效果

Clinical Effect of Gushu Decoction Combined with Western Medicine in Treatment of Elderly Patients with Osteoporotic Thoracolumbar Compression Fractures Undergoing Posterior Percutaneous Vertebroplasty

目的:分析骨疏汤联合西药用于老年骨质疏松性胸腰椎压缩性骨折行后路经皮椎体成形术后的效果。方法:选取2020年5月—2022年5月于宁乡市中医医院行后路经皮椎体成形术的110例老年骨质疏松性胸腰椎压缩性骨折患者作为研究对象,随机分为对照组与试验组,各55例。对照组应用碳酸钙D3联合鲑降钙素注射液治疗,试验组在对照组基础上给予骨疏汤。对比两组治疗效果,疼痛、腰椎功能和骨质疏松情况,伤椎情况及并发症发生情况。结果:试验组治疗总有效率高于对照组,差异有统计学意义(P<0.001)。治疗后,两组视觉模拟评分法、Oswestry功能障碍指数评分低于治疗前,试验组低于对照组,两组骨密度高于治疗前,试验组高于对照组,差异有统计学意义(P<0.05)。治疗后,两组椎体前缘丢失高度、伤椎Cobb角度均小于治疗前,且观察组小于对照组,差异有统计学意义(P<0.05)。试验组并发症总发生率低于对照组,差异有统计学意义(P=0.002)。结论:老年骨质疏松性胸腰椎压缩性骨折应用骨疏汤治疗效果突出,有利于改善患者骨质质量,减轻躯体痛感,缩短骨折愈合的时间,促进胸腰椎功能恢复,减少骨成分丢失。

Objective:To analyze the effect of Gushu decoction combined with western medicine in the treatment of senile osteoporotic thoracolumbar compression fractures undergoing posterior percutaneous vertebroplasty.Methods:A total of 110 elderly patients with osteoporotic thoracolumbar compression fractures who underwent posterior percutaneous vertebroplasty in Ningxiang Traditional Chinese Medicine Hospital from May 2020 to May 2022 were selected as the study subjects.They were randomly divided into control group and experimental group,with 55 cases in each group.The control group was treated with calcium carbonate and vitamin D3 combined with salmon calcitonin injection.The experimental group was treated with Gushu decoction on the basis of the control group.The treatment effects,pain,lumbar function and osteoporosis,vertebral injury and complications in the two groups were compared.Results:The total effective rate of treatment in the experimental group was higher than that in the control group,and the difference was statistically significant(P<0.001).After treatment,the visual analogue scale score and Oswestry dysfunction index score in the two groups were lower than those before treatment,the experimental group was lower than the control group,the bone mineral density in the two groups was higher than that before treatment,and the experimental group was higher than the control group,and the difference was statistically significant(P<0.05).After treatment,the anterior vertebral height loss and Cobb angle of the injured vertebral body in two groups were smaller than those before treatment,and the observation group was smaller than the control group,and the difference was statistically significant(P<0.05).The total incidence of complications in the experimental group was lower than that in the control group,and the difference was statistically significant(P=0.002).Conclusion:The Gushu decoction has obvious effect in the treatment of senile osteoporotic thoracolumbar compression fractures,it is beneficial to improve the bone quality of patients,reduce somatic pain,shorten the time of fracture healing,promote the recovery of thoracolumbar spine function,and reduce the loss of bone components.