内镜下黏膜下剥离术治疗消化道肿瘤术后发生食管良性狭窄的影响因素

Influencing Factors for the Occurrence of Benign Esophageal Stricture After Endoscopic Submucosal Dissection in the Treatment of Gastrointestinal Tumors

目的探讨消化道肿瘤内镜下黏膜下剥离术后食管良性狭窄的影响因素。方法90例行内镜下黏膜下剥离术治疗的消化道肿瘤患者,参考手术结局分为狭窄组(术后食管良性狭窄)和无狭窄组(术后未发生食管良性狭窄)。统计两组的临床特征资料,分析术后食管良性狭窄的主要影响因素。结果单因素分析和多因素分析结果显示,肿瘤直径≥50mm、病变纵向长度、病变环周直径及浸润深度sm1均为术后食管良性狭窄的主要影响因素(P<0.05)。结论消化道肿瘤患者内镜下黏膜下剥离术后食管良性狭窄的发生与肿瘤直径、病变直径、浸润深度密切相关。

Objective To explore the influencing factors of benign esophageal stricture after endoscopic submucosal dissection for gastrointestinal tumors.Methods 90 patients with gastrointestinal tumors who underwent endoscopic submucosal dissection were divided into the stenosis group(postoperative benign esophageal stenosis)and the non-stenosis group(without postoperative benign esophageal stenosis)according to the surgical outcome.The clinical characteristics of the two groups were counted,and the main influencing factors of postoperative benign esophageal stenosis were analyzed.Results Univariate analysis and multivariate analysis showed that tumor diameter≥50 mm,longitudinal length of lesion,circumferential diameter of lesion and infiltration depth sml were the main influencing factors of postoperative benign esophageal stenosis(P<0.05).Conclusions The occurrence of benign esophageal stricture after endoscopic submucosal dissection in patients with gastrointestinal tumors is closely related to tumor diameter,lesion diameter and depth of infiltration.