虚拟现实技术联合虚拟场景暴露反应/仪式阻断治疗技术对女性强迫症患者治疗依从性的影响

Effect of VR virtual scene ERP on treatment compliance of female patients with obsessive-compulsive disorder

目的探讨虚拟现实(VR)技术联合虚拟场景暴露反应/仪式阻断治疗技术(ERP)对女性强迫症患者治疗依从性的影响。方法回顾性分析2020年8月—2022年8月在金华市第二医院接受诊治的80例强迫症女性患者的临床资料,其中40例实施常规ERP治疗,设为对照组;40例实施VR技术虚拟场景ERP治疗,设为观察组。比较两组治疗依从性、治疗前后症状严重程度和认知功能及治疗发生不良反应情况。结果观察组治疗依从性97.50%高于对照组85.00%(χ^(2)=3.914,,P<0.05)。观察组治疗2周、4周和8周后Y-BOCS评分分别为(14.62±1.64、12.51±1.27、7.81±2.86)均低于对照组(15.63±2.68、13.24±0.84、9.64±3.49),差异有统计学意义(P<0.05)。观察组治疗2周、4周及8周后MoCA-B评分分别为(15.63±2.68、13.24±0.84、9.64±3.49)均高于对照组(14.62±1.64、12.51±1.27、7.81±2.86),差异有统计学意义(P<0.05)。观察组治疗第5~8周的PDSS评分分别为(13.52±2.45、9.85±1.13、9.39±0.67、7.65±0.98)均低于对照组(13.64±2.61、10.26±0.97、9.76±0.54、8.64±1.24),差异有统计学意义(P<0.05)。结论给予强迫症女性患者VR技术虚拟场景ERP治疗可提升其治疗依从性,促进其强迫症状和认知缺陷的改善,治疗不良反应程度较轻,患者接受程度较高。

Objective This study investigated the effects and compliance of female patients forced to undergo virtual reality(VR)virtual scene exposure response/ritual blocking therapy(ERP).Methods The clinical data of 80 female patients with OCD who received diagnosis and treatment in our hospital from August 2020 to August 2022 were retrospectively analyzed.40 of them received routine ERP treatment and were set as the control group.40 patients underwent VR virtual scene ERP treatment and were assigned as the observation group.The treatment compliance,severity of symptoms and cognitive function before and after treatment,and the incidence of adverse reactions were compared between the two groups.Results The treatment compliance of observation group was 97.50%higher than that of control group 85.00%(χ^(2)=3.914,P<0.05).Affer 2,4 and 8 weeks of treatment,Y-B0CS scores in the observation group were(14.62±1.64,12.51±1.27,7.81±2.86)lower than those in the control group(15.63±2.68,13.24±0.84,9.64±3.49),and the difference was statistically significant(P<0.05).After 2,4 and 8 weeks of treatment,MoCA-B scores in the observation group were(15.63±2.68,13.24±0.84,9.64±3.49)higher than those in the control group(14.62±1.64,12.51±1.27,7.81±2.86),and the difference was statistically significant(P<0.05).The PDSS scores of the observation group were(13.52±2.45,9.85±1.13,9.39±0.67,7.65±0.98)lower than those of the control group(13.64±2.61,10.26±0.97,9.76±0.54,8.64±1.24)at the 5th to 8th week of treatment,respectively.The difference was statistically significant(P<0.05).Conclusion VR virtual scene ERP treatment for female patients with OCD can improve their treatment compliance,promote the improvement of obsessive-compulsive symptoms and cognitive defects,and the degree of adverse'reactions is relatively mild,and the degree of acceptance is high.