基于德尔菲法构建《中国慢性诱导性荨麻疹诊治专家共识(2023)》

Construction of “Expert consensus on diagnosis and treatment of chronic inducible urticaria in China(2023)”based on the Delphi method

目的基于德尔菲法构建《中国慢性诱导性荨麻疹诊治专家共识(2023)》,并为共识的构建提供方法学依据。方法充分检索并评估慢性诱导性荨麻疹研究相关的文献,撰写《中国慢性诱导性荨麻疹诊治专家共识(2023)》初稿,并设计专家咨询问卷。选取有代表性的25位专家,严格按照德尔菲法的研究方法,以电子问卷的形式进行两轮专家问卷函询,并对共识稿件内容进行修改完善。结果两轮问卷收回率均为100%,专家权威系数为0.92±0.09。第1轮问卷结果中有9个条目变异系数(CV值)>20%,3个条目的认可度平均值<7分;第2轮问卷结果中所有条目的CV值均<15%,原有认可度平均值<7分的3个条目认可度均升至7分以上,且所有条目的中位数均≥8分。两轮问卷结果的信度分析显示,Cronbachα系数和标准化Cronbachα系数均>0.9;两轮问卷结果的一致性Kendall协调系数检验结果均P<0.001,第1轮问卷结果的Kendall协调系数为0.170,第2轮为0.219。结论应用德尔菲法构建的《中国慢性诱导性荨麻疹诊治专家共识(2023)》具有很好的代表性、权威性和可靠性;本研究也为共识的制定和研究提供了方法学参考。

Objective e To construct"Expert consensus on diagnosis and treatment of chronic inducible urticaria in China(2023)"based on the Delphi method,and to provide a methodological basis for consensus construction.Methods After systematic search and evaluation of the literature related to chronic inducible urticaria,the first draft of"Expert consensus on diagnosis and treatment of chronic inducible urticaria in China(2023)"was written,and a questionnaire was designed for expert consultation.A representative sample of 25 experts was selected to conduct two rounds of correspondence consultation via electronic questionnaire in strict accordance with the Delphi method.and the content of the consensus was revised and improved according to the consultation results.Results The response rates in the two rounds of questionnaire consultation were both 100%,and the expert authority coefficient was 0.92±0.09.In the first round of consultation,the coefficients of variation(CV values)of 9 items were greater than 20%,and the mean agreement degree of 3 items was less than 7 points;in the second round of consultation,the CV values of all items were less than 15%,the agreement degree of the above 3 items whose mean agreement degree was less than 7 points in the first round of consultation all rose to over 7 points,and the median agreement degree of all items was greater than or equal to 8 points.Reliability analysis of the two rounds of questionnaire results showed that the Cronbachαcoefficient and standardized Cronbachαcoefficient were both greater than O.9:the P values in the agreement tests by using Kendall's coefficient of concordance for the two rounds of questionnaire results were both less than 0.001,and the Kendall's coefficients of concordance were 0.170 and 0.219 in the first and second rounds of questionnaire consultation,respectively.Conclusion The Delphi method-based"Expert consensus on diagnosis and treatment of chronic inducible urticaria in China(2023)"is highly representative,authoritative and reliable;this study also provides a methodological reference for the formulation and research of consensus.