基于癌毒病机理论辨治卵巢癌

Differentiation and treatment of ovarian cancer based on the pathogenesis theory of cancer toxin

癌毒病机理论是在传承国医大师周仲瑛“癌毒”学说的基础上创建的癌毒病机辨治体系,其以癌毒为中心,阐述了肿瘤发生发展的病机演变规律,为肿瘤的辨证论治提供了重要指导。癌毒病机理论认为,卵巢癌的病位在胞宫、冲任,与肝、肾密切相关。其主要病理因素为虚、瘀、湿、毒,其中,以瘀为主,而夹毒。其核心病机为肝肾两虚,湿浊瘀毒。病机演变过程始于肝肾两虚,继而精、气、血亏虚,脉道失养,因虚致瘀,阻滞气机,津液失布,湿浊内生,湿瘀互结,癌毒内生,癌毒损正,又加重肝肾两虚。临床治疗上,当以抗癌解毒为核心,祛瘀消癥为关键,利湿化浊为要点,培补肝肾为根本。以癌毒病机理论为依据,结合临床实践,探讨卵巢癌的病理因素、核心病机、病机演变规律及治则治法,以期为卵巢癌的辨证论治提供新思路,从而进一步提高中医药治疗卵巢癌的临床疗效。

The pathogenesis theory of cancer toxin is a system for differentiating and treating cancer toxin established by our team on the basis of the academic thought of cancer toxin proposed by Zhou Zhongying,a master of traditional Chinese medicine.It elaborates the pathogenesis and evolution rule of tumor occurrence and development with cancer toxin as the center,and provides important guidance for clinical tumor differentiation and treatment.According to the pathogenesis theory of cancer toxin,ovarian cancer is located in the uterus and thoroughfare and controlling vessels,and closely related to the liver and kidney.The pathological factors mainly include deficiency,blood stasis,dampness and toxin,among which blood stasis is the focus with toxin contained.The core pathogenesis is deficiency of both liver and kidney and dampness,blood stasis,cancer toxin.The pathogenesis begins with deficiency of the liver and kidney.Then,because of the development of essence,qi and blood deficiency,blood vessels lack nutrition,leading to qi stagnation and blood stasis.As the disease progresses,the body fluid distribution is changed and endogenous dampness combines with blood stasis,which induces the formation of cancer toxin.At last,cancer toxin damages vital qi and aggravates the liver and kidney deficiency.Treatment should focus on the core principle of anti⁃cancer and detoxification.Removing blood stasis and dispersing dampness are key objective,with nourishment of the liver and kidney as the basis.Based on the pathogenesis theory of cancer toxin and clinical practice,this article explores the pathological factors,core pathogenesis,pathogenesis evolution rules,therapeutic principles and methods of ovarian cancer.This article is mainly aimed at providing new ideas for syndrome differentiation and treatment of ovarian cancer and to further improve the clinical efficacy of ovarian cancer treatment with traditional Chinese medicine.