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链脲霉素诱导2型糖尿病雄性大鼠核糖与核糖激酶的变化

Changes in Ribose and Ribokinase in STZ-induced Type 2 Diabetic Rat
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摘要 Dear Editor,Type 2 diabetes mellitus(T2DM)is a metabolic disorder that impacts multiple organs including brain activity through mechanisms such as glucose toxicity,insulin resistance,mitochondrial dysfunction,and vascular damage^([1-2]).As described by Su and his colleagues^([3])in 2013,type 2 diabetics had abnormally high levels of urine ribose,suggesting that the patients suffered from not only glucose metabolism disorders,but also ribose metabolism disorders^([4]).
作者 康念欣 于乐祥 刘缨 赫荣乔 KANG Nian-Xin;YU Le-Xiang;LIU Ying;HE Rong-Qiao(School of Life Sciences,Beijing University of Chinese Medicine,Beijing 102401,China;Institute of Biophysics,University of Chinese Academy of Sciences,Beijing 100101,China)
出处 《生物化学与生物物理进展》 SCIE CAS CSCD 北大核心 2023年第5期1235-1238,共4页 Progress In Biochemistry and Biophysics
基金 supported by grants from Beijing Brain Project(Z161100000217141) the Fundamental Research Funds for the Central Universities(2020-JYB-ZDGG-051)。
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