药物治疗联合前庭训练治疗急性前庭神经炎的临床疗效

CLINICAL EFFECT OF DRUG THERAPY COMBINED WITH VESTIBULAR TRAINING ON ACUTE VESTIBULAR NEURITIS

目的 研究常规药物倍他米松、甲磺酸倍他司汀、苯海拉明等配合前庭功能训练的同步治疗对于急性前庭神经炎患者的临床治疗效果。方法 研究对象来源于2020年1月—2021年12月唐山市人民医院神经内二科收治的85例急性前庭神经炎患者,按照治疗方式不同分为对照组和观察组,前者41例给予常规药物倍他米松、甲磺酸倍他司汀、苯海拉明等治疗,后者44例给予常规药物治疗的同时对患者配合同步的前庭功能训练治疗。治疗结束后比较二组患者治疗后眩晕症状出现的频率及严重程度;比较二组患者治疗前后眩晕残障程度评定量表(DHI)评分和前庭症状指数量表(VSI)评分;比较二组患者治疗后疗效的差异。结果 治疗后观察组患者出现较高频率眩晕症状(除去极少频率的偶尔或经常频率)的人数低于对照组;治疗后观察组患者出现较严重程度眩晕症状(除去轻度的中重度程度)的人数低于对照组;治疗后观察组患者眩晕残障程度评定量表评分明显低于对照组;治疗后观察组患者前庭症状(头晕、平衡障碍、恶心及视觉敏感)各项评分均低于对照组;观察组治疗后治疗效果有效例数及明显有效例数的患者(42例,总有效率95.45%)明显高于对照组(33例,总有效率80.49%),以上差异均有统计学意义(均P<0.05)。结论 常规药物倍他米松、甲磺酸倍他司汀、苯海拉明等治疗配合前庭功能训练的同步治疗急性前庭神经炎患者,对于改善前庭功能、缓解较高频率以及中重度的眩晕症状起到了关键性作用,整体的治疗效果得到了提升,明显提升了该类患者的预后及其生活质量。

Objective To study the clinical effect of simultaneous treatment of betamethasone, betastine mesylate, diphenhydramine and other conventional drugs combined with vestibular function training on patients with acute vestibular neuritis. Methods The study subjects were from eighty-five patients with acute vestibular neuritis admitted to the Second Department of Neurology of Tangshan People's Hospital from January 2020 to December 2021.According to different treatment methods, they were divided into two groups: control group and observation group.forty-one patients in the former group were treated with conventional drugs such as betamethasone, betastine mesylate and diphenhyramine.The latter forty-four patients were treated with conventional drug therapy and simultaneous vestibular function training.After treatment, the relevant indicators of the two groups were compared, such as the frequency and severity of vertigo symptoms between the two groups.We compare the dizziness handicap inventory(DHI) scores of the two groups before and after treatment.The scores of vestibular symptom index(VSI) before and after treatment were compared between the two groups.The difference of curative effect between the two groups after treatment was compared. Results After treatment, the number of patients in observation group with high frequency of vertigo symptoms(except occasional or frequent frequency with very little frequency) was lower than that in control group.After treatment, the number of patients in observation group with more severe vertigo symptoms(except mild moderate to severe degree) was lower than that in control group.After treatment, the score of vertigo disability rating scale in observation group was significantly lower than that in control group.After treatment, the scores of vestibular symptoms(dizziness, balance disorder, nausea and visual sensitivity) in observation group were lower than those in control group.The number of effective cases and obvious effective cases in observation group after treatment(forty-two cases, total effective rate of 95.45%) was significantly higher than that in control group(hirty-three cases, total effective rate of 80.49%),and all of the difference were statistically significant(P<0.05). Conclusion Conventional drugs, such as betamethasone, betastine mesylate and diphenhydramine, combined with vestibular function training, played a key role in improving vestibular function and alleviating frequent and moderate to severe vertigo symptoms in patients with acute vestibular neuritis.The overall therapeutic effect was improved, and the prognosis and quality of life of these patients were significantly improved.