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基于专利地图的全球肠道微生态产业研发态势分析

Research and Development Trend Analysis of Global Intestinal Microecology Industry Based on Patent Map
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摘要 人体肠道微生态在维持人体健康和疾病的发生发展过程中扮演着重要角色。世界面临的如新冠疫情等重大传染病的暴发流行、食源性疾病、致病性耐药“超级细菌”等问题趋于严峻,威胁着人类健康。因此,利用专利大数据,开展基于专利地图的全球肠道微生态产业研发态势分析,对肠道微生态产业发展方向做出初步判断、厘清研发热点具有重要实践意义。基于专利地图,重点从专利管理图和专利技术图维度分析2011—2021年全球肠道微生态产业专利的申请趋势、公开国别、发明人、技术构成、研发热点、核心专利技术路径演进趋势和重点机构竞争影响力。研究发现,全球肠道微生态产业专利申请量呈逐渐快速增长趋势,2020年达到第二个高峰,未来将继续高速增加,其中中国是当前专利申请、受理和公开占比最高的国家,申请量前10第一发明(设计)人主要来自中国;拟杆菌|细菌领域为全球研发热点,各国研发热点各有千秋,整体上形成了优势互补格局。 The human intestinal microbiome plays an important role in maintaining human health and the occurrence and development of diseases.The world is faced with some serious infectious diseases such as the novel coronavirus epidemic,and foodborne diseases,pathogenic drug-resistant“superbugs”and other problems are becoming more serious,threatening human health.Therefore,it is of great practical significance to use patent big data to carry out the analysis of the research and development(RD)situation of the global intestinal microecology industry based on the patent map,make a preliminary judgment on the development direction of the intestinal microecology industry,and clarify the RD hotspots.Based on the patent map,this paper focuses on analyzing the patent application trend,disclosure of applicants'nations,inventor,technical composition,RD hotspots,core patent technology path evolution trend and competitive influence of key institutions from 2011 to 2021 and from the dimensions of patent management map and patent technology map.The study found that the number of patent applications in the global intestinal microecology industry showed a gradual and rapid growth trend,reaching the second peak in 2020,and will continue to increase rapidly in the future.China is the country with the highest proportion of patent applications,acceptance and disclosure,and the top 10 first inventors(designers)in terms of application volume are mainly from China.The field of bacteroides|bacteria is a global RD hotspot,the RD hotspots of various countries have their own merits,and the overall complementary advantages have been formed.
作者 宇岩 王春明 薛亮 汤正午 祝林 褚英敏 张丽佳 YU Yan;WANG Chun-ming;XUE Liang;TANG Zheng-wu;ZHU Lin;CHU Ying-min;ZHANG Li-jia(Guangdong Science&Technology Library(Information Research Institute of Guangdong Academy of Sciences),Guangzhou 510070,China;Institute of Microbiology,Guangdong Academy of Sciences,Guangzhou 510070,China)
出处 《中国生物工程杂志》 CAS CSCD 北大核心 2023年第5期85-93,共9页 China Biotechnology
基金 广州市基础研究计划基础与应用基础研究(2023A04J1052) 中国工程科技发展战略广东研究院咨询研究(2019-GD-4)资助项目。
关键词 肠道微生物 肠道微生态 专利地图 产业格局 Intestinal microorganisms Intestinal microecology Patent map Industrial pattern
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