老年肺癌患者合并衰弱的研究进展

Progress in research on complicated frailty in elderly patients with lung cancer

肺癌是我国发病率和死亡率最高的癌症,给医疗保健系统带来了巨大压力。老年人是肺癌的高发人群,老年肺癌患者易发生衰弱,衰弱会增加其术后并发症、放化疗不良反应、全因死亡风险、住院时间及再入院率,严重影响预后。而衰弱具有一定的可逆性,因此早期发现和采取相应的干预措施至关重要。本文对老年肺癌患者衰弱的危险因素、与不良健康结局的相关性及干预策略进行了综述,以便临床上尽早识别老年肺癌患者的衰弱状态,并进行早期干预,从而改善患者预后。

Lung cancer is the cancer with the highest morbidity and mortality in China,posing huge pressure on the healthcare system.The elderly have a high incidence of lung cancer.Elderly lung cancer patients are prone to frailty,which will increase post-operative complications,adverse reactions to radiotherapy and chemotherapy,the risk of all-cause death,length of hospital stay and readmission rate,and seriously affect prognosis.Frailty is reversible,and early detection and intervention are crucial.In this article,we reviewed the risk factors of frailty,its correlation with adverse health outcomes,and its intervention strategies in the elderly lung cancer patients,for its early identification and timely interventions clinically,thus improving patients′prognosis.