基于联萘酚的荧光探针对缬氨酸的手性识别研究

Chiral Recognition of Valine by Fluorescence Probe Based on Binaphthol

以1,1’-联二萘酚为手性原料合成一种新型的手性荧光探针分子。合成路线简短,易于纯化。实验研究表明,该荧光探针可以对苏氨酸的两种对映异构体进行手性识别,两种异构体的荧光强度比可以达到I_D/I_L=5.1,同时,探针分子也可以用于测定缬氨酸的对映体组成。

A novel chiral fluorescent probe was synthesised with 1,1’-binaphthol as chiral sources,which featured concise synthetic route,simple purification.The experimental results showed that the fluorescent probe could recognize the two enantiomers of threonine,and the fluorescence intensity ratio of the two isomers could reach ID/IL=5.1.At the same time,the probe molecule could also be used to determine the enantiomeric composition of valine.