慢性炎性脱髓鞘性多发性神经根神经病诊疗要点解析

The key points in diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy

诊断慢性炎性脱髓鞘性多发性神经根神经病时,需要寻找关键的诊断依据,包括临床特点、电生理脱髓鞘改变、脑脊液蛋白细胞分离现象、周围神经影像学表现、周围神经病理改变以及免疫治疗效果等。每一个诊断依据,都必须与临床背景以及其他证据综合分析,才能真正发挥作用,以避免漏诊而延误治疗,并防止过度诊断导致不必要的免疫治疗。

The diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy relies on clinical features,demyelinating changes on motor and sensory nerve conduction studies,elevated cerebrospinal fluid protein,peripheral nerve image,nerve pathology,and response to immune therapy.Each diagnostic proof should be interpreted in light of clinical background and other findings,to avoid misdiagnosis or overdiagnosis,treatment delay or unnecessary treatment with immunotherapy.