锆、钛介导的烯烃、炔烃硼氢化

Zirconium and Titanium Mediated Hydroboration of Alkenes and Alkynes

过渡金属催化的烯烃、炔烃硼氢化反应是制备硼酸酯类化合物最为有效的方法之一,该反应具有100%的原子经济性,原料简单易得,产物多样性可调等优点.已知的金属催化剂大都依赖于铑、铱、钯、铂、钴、铁、铜等后过渡金属,而使用前过渡金属锆、钛作为催化剂的反应体系则鲜有报道.总结了锆、钛介导的(化学计量与催化量)烯烃、炔烃硼氢化反应的研究现状,并对今后锆、钛催化的烯烃、炔烃硼氢化反应的发展进行了展望.

The transition metal-catalyzed hydroboration of alkenes and alkynes is one of the most efficient way for the production of boronate esters.This type of reaction is 100%atom economic,the starting material is readily available,and the products are diverse.It is noticed that most of the known catalytic systems are based on late-transition-metals such as Rh,Ir,Pd,Pt,Co,Fe and Cu.The use of early-transition-metals of zirconium and titanium,on the other hand,is very scarce.In this short review,the development of application in zirconium and titanium mediated hydroboration of alkene and alkyne is summarized,and the research trends of this area are also discussed.