摘要
Brain asymmetry,involving structural and functional differencesbetween the two hemispheres,is a major organizational principle ofthe human brain.The structural and functional connectivity withineach hemisphere defines the hemispheric network or connectome.Elucidating left-right differences of the hemispheric network providesopportunities for brain asymmetry exploration.This review examinesthe asymmetry in the hemispheric white matter and functionalnetwork to assess health and brain disorders.In this article,the brain asymmetry in structural and functional connectivity includingnetwork topologies of healthy individuals,involving brain cognitivesystems and the development trend,is highlighted.Moreover,theabnormal asymmetry of the hemispheric network related to cognition changes in brain disorders,such as Alzheimer’s disease,schizophrenia,autism spectrum disorder,attention deficit hyperactivity disorder,and bipolar disorder,is presented.This review suggests that thehemispheric network is highly conserved for measuring human brain asymmetries and has potential in the study of the cognitivesystem and brain disorders.
基金
This work was supported by the National Natural Science Foundation of China(Grant Nos.62176177,61906130)
the National Key R&D Program of China(Grant No.2018AAA0102604)
the Natural Science Foundation of Shanxi(Grant No.20210302123112)
the Research Project Supported by Shanxi Scholarship Council of China(Grant No.2021-039).
