SARS-CoV-2对女性生殖健康的研究进展

Research progress of SARS-CoV-2 on female reproductive health

严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome corona virus 2,SARS-CoV-2)在全球迅速蔓延并引发了世界大流行。目前SARS-CoV-2是否对女性生育力产生潜在不利影响尚不明确,后续需要更多的证据支持。对妊娠合并SARS-CoV-2的初步研究显示,SARS-CoV-2可能会增加子痫前期、早产和胎膜早破的风险,但似乎早期流产风险不高,感染SARS-CoV-2是否垂直传播而影响下一代,目前暂不清楚,还需要更多的证据支持。随着SARS-CoV-2的流行,SARS-CoV-2疫苗的研发和临床试验在全球范围内广泛开展,目前研究表明接种SARS-CoV-2疫苗可能不会对女性的生殖系统存在不利影响。本文结合近几年来关于SARS-CoV-2对女性生殖健康的研究进展进行简要综述。

Severe acute respiratory syndrome corona virus 2(SARS-CoV-2)has spread rapidly around the world and triggered a worldwide pandemic.Whether SARS-CoV-2 potentially adversely affects female fertility is unclear now,and more evidence is needed to support the follow-up.Preliminary studies of combined SARS-CoV-2 in pregnancy have found that SARS-CoV-2 may increase the risk of preeclampsia,preterm delivery,and premature rupture of membranes,but does not appear to be associated with a high risk of early miscarriage.Whether SARS-CoV-2 infection will be vertically transmitted and affect the next generation is unclear and requires more evidence supports.With the prevalence of SARS-CoV-2,the development and clinical trials of SARS-CoV-2 vaccine are widely conducted worldwide,and current studies suggest that SARS-CoV-2 vaccination may not have adverse effects on the reproductive system of women.This article briefly reviewed the progress of research on SARS-CoV-2 on female reproductive health in the context of recent years.