针药结合治疗寒湿型类风湿性关节炎临床研究

Clinical Study on the Treatment of Cold-Dampness Rheumatoid Arthritis with Combination of Acupuncture and Medicine

目的:观察针药结合治疗寒湿型类风湿性关节炎的临床疗效。方法:选取2020年1月至2021年12月收治的寒湿型类风湿性关节炎患者60例为研究对象,按照随机数字表法分为观察组和对照组,每组30例。对照组采用温针灸疗法治疗,观察组在对照组治疗的基础上给予中药熏蒸治疗。观察两组患者治疗前后视觉模拟评分(visual analogue score,VAS)、疾病活动评分(disease activity score,DAS)、晨僵持续时间、关节压痛计数、关节肿胀计数、超敏C反应蛋白(C-reactive protein,CRP)、血沉(erythrocyte sedimentation rate,ESR)、类风湿因子(rheumatoid factor,RF)变化情况及临床疗效。结果:观察组有效率为93.33%,对照组有效率为70.00%,观察组高于对照组,差异有统计学意义(P<0.05)。观察组治疗后患者总体评分、医生对患者疾病总体状况评分、DAS评分低于对照组,差异具有统计学意义(P<0.05)。观察组治疗后关节压痛、肿胀关节计数、晨僵时间低于对照组,差异具有统计学意义(P<0.05)。观察组治疗后CRP、ESR、RF水平低于对照组,差异具有统计学意义(P<0.05)。结论:针药结合治疗寒湿型类风湿性关节炎有较好的临床疗效,能改善患者临床症状、体征,降低血清炎症因子、类风湿因子水平。

Objective:To observe the clinical efficacy of combination of acupuncture and medicine on cold-dampness rheumatoid arthritis(RA).Methods:A total of 60 patients with RA with cold-dampness syndrome admitted from January 2020 to December 2021 were selected as the study subjects.Afer average grouping,the control group was treated with warming needle moxibustion,while the observation group was treated with Chinese medicinal fumigation on the basis of the control group.The changes of visual analog score(VAS),disease activity score(DAS),duration of morning stiffness,joint tenderness count,joint swelling count,C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),rheumatoid factor(RF)and clinical efficacy of the two groups were observed before and after treatment.Results:The effective rate of the observation group was 93.33%,while that of the control group was 70.00%.The observation's group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the patient's overall score,doctor's overall rating of the patient's disease condition score,and DAS score of the observation group were lower than those of the control group,and all the differences were statistically significant(P<0.05);The observation group had lower joint tenderness,swelling joint count,and morning stffness time compared with the control group,and allthe differences were statistically significant(P<0.05);The levels of CRP,ESR,and RF of the observation group were lower than those of the control group,and all the differences were statistically significant(P<0.05).Conclusion:The combination of acupuncture and medicine has a good clinical effect on RA of cold-dampness type,can improve the clinical symptoms and signs of patients,and reduce the levels of serum inflammatory factors and rheumatoid factor.