正念疗法对青少年抑郁症患者负面情绪、认知功能及生活质量的影响

Effect of Mindfulness Therapy on Negative Emotions,Cognitive Function,and Quality of Life in Adolescent Depression Patients

目的:探讨正念疗法对青少年抑郁症患者负面情绪、认知功能及生活质量的影响。方法:选取徐州市东方人民医院2020年6月—2022年6月接收的80例青少年抑郁患者为研究对象,根据随机分组法将其分为对照组和观察组,各40例。对照组采用临床常规的抗抑郁药物治疗,观察组在对照组基础上加入正念疗法,比较两组治疗前后的抑郁程度、负面情绪、认知功能、生活质量。结果:治疗后,观察组汉密尔顿抑郁量表(HAMD)评分、正性与负性情绪量表(PANAS)评分均低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组威斯康星卡片分类测验(WCST)中总应答执行次数、非坚持性错误应答数、坚持性错误数优于对照组,差异有统计学意义(P<0.05)。治疗后,观察组世界卫生组织生存质量测定量表简表(WHOQOL-BREF)各维度评分及总分均高于对照组,差异有统计学意义(P<0.05)。结论:正念疗法联合常规药物治疗,可以明显缓解青少年抑郁症负面情绪,改善患者认知功能,促进康复,提高生活质量。

Objective:To explore the effect of mindfulness therapy on negative emotions,cognitive function,and quality of life in adolescent depression patients.Method:A total of 80 adolescent depression patients admitted to Xuzhou Dongfang People's Hospital from June 2020 to June 2022 were selected as the study objects,they were randomly divided into a control group and an observation group,with 40 patients in each group.The control group received routine clinical antidepressant drugs therapy,while the observation group received mindfulness therapy on the basis of control group.The depression level,negative emotions,cognitive function,and quality of life of the two groups were compared before and after treatment.Result:After treatment,the Hamilton depression scale(HAMD)score and positive and negative affect scale(PANAS)score in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the total response execution times,non persistent errors and persistent errors in the Wisconsin card sorting test(WCST)in the observation group were better than those in the control group,the differences were statistically significant(P<0.05).After treatment,all dimensions and total scores on the World Health Organization quality of life scale(WHOQOL-BREF)in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Mindfulness therapy combined with routine drugs can significantly alleviate negative emotions in adolescent depression,improve cognitive function,promote recovery,and improve quality of life.