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Beneficial and detrimental effects of processed dietary fibers on intestinal and liver health:health benefits of refined dietary fibers need to be redefined! 被引量:2

加工膳食纤维对肠道和肝脏健康的益处与损害:精制膳食纤维的健康获益需重新定义!
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摘要 Consumption of processed foods—which are generally composed of nutritionally starved refined ingredients—has increased exponentially worldwide.A rise in public health awareness that low fiber intake is strongly linked to new-age disorders has spurred food manufacturers to fortify processed foods with refined dietary fibers(RDFs).Consumption of whole foods rich in natural fibers undoubtedly confers an array of health benefits.However,it is not clear whether RDFs extracted from the whole plant,kernel,and fruit peels exert similar physiological effects to their naturally occurring counterparts.Recent studies caution that RDFs are not universally beneficial and that inappropriate consumption of RDFs may risk both gastrointestinal and liver health.Herein,we briefly summarize the beneficial and detrimental effects of RDFs on digestive health and discuss the contribution of metabolites derived from microbial fermentation of RDFs in driving such positive or negative health outcomes. 加工食品的食用量在全球范围内呈现一个指数增长,而这些加工食品中多是一些营养匮乏的精加工配料。随着公众健康意识的增强,大家认识到,当前许多疾病的发生都与纤维摄入不足密切相关,而食品制造商则开始在加工食品中添加一些精制膳食纤维(RDFs)以满足公众的健康需求。食用富含纯天然纤维的食品无疑会带来一系列的健康益处,但从植物、谷物、果皮中提取出来的RDFs是否与这些纯天然的纤维具有相似的生理作用,目前尚不明了。最新研究认为,RDFs并非总是有益的,不当摄入甚至可能危害肠道和肝脏健康。在此,我们概述了RDFs对消化系统的益处与害处,并探讨了RDFs通过微生物发酵的代谢产物对肠道和肝脏健康所产生的有益或不利影响。
出处 《Gastroenterology Report》 SCIE EI 2020年第2期85-89,I0001,共6页 胃肠病学报道(英文)
基金 supported by grants from the National Institutes of Health[R01CA219144] M.V.-K.V.S.is supported by a Career Development Award[ID#597229]from the Crohn’s&Colitis Foundation(CCF).
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