摘要
龟分枝杆菌感染可继发于外科手术操作、外伤等,也可能与使用免疫抑制药物相关。临床表现与病理表现缺乏特异性,需抗生素联合足疗程治疗。本文报道一例面部肿胀性红斑狼疮,治疗数天后面部原皮疹部位继发红斑、丘疹、脓疱,通过皮肤组织活检、qPCR测序确诊龟分枝杆菌感染,患者经克拉霉素、利奈唑胺药物联合治疗后好转。
Mycobacterium chelae infection can be occurred after surgery or trauma,and may also be related to the use of immunosuppressive medicine.The manifestations lacks of specificity.It requires a combination of antibiotics and a full course of treatment.We report a case of facial tumescent lupus erythematosus complicated with Mycobacterium chelae infection.The diagnosis was confirmed by skin biopsy and qPCR sequencing.The patient was cured by clarithromycin and linezolid.
作者
彭一然
孙乐乐
暴芳芳
周桂芝
卢宪梅
刘永霞
刘红
张福仁
PENG Yiran;SUN Lele;BAO Fangfang;ZHOU Guizhi;LU Xianmei;LIU Yongxia;LIU Hong;ZHANG Furen(Shandong Provincial Hospital for Skin Diseases&Shandong Provincial Institute of Dermatology and Venerology,Shandong First Medical University&Shandong Academy of Medical Sciences,Jinan 250022,China)
出处
《中国麻风皮肤病杂志》
2023年第7期512-515,共4页
China Journal of Leprosy and Skin Diseases
基金
山东省“泰山学者青年专家计划”(编号:tsqn201812124)
山东第一医科大学学术提升计划(编号:2019RC007)。
关键词
非典型分枝杆菌
龟分枝杆菌
肉芽肿
测序
克拉霉素
利奈唑胺
Non-tuberculous Mycobacteria
Mycobacterium chelae
granuloma
sequencing
clarithromycin
linezolid
