肺癌立体定向放射治疗中的运动管理研究现状

Research on motion management in stereotactic body radiotherapy for lung cancer

立体定向放射治疗作为治疗临床上不适合手术或拒绝手术的早期非小细胞肺癌患者的首选方式,是一种分割次数较少、单次放疗剂量大的大分割放射治疗方法。因此,对靶区位置的精度及重复性具有较高要求。针对此,临床上采用影像引导技术、合适的固定装置以及呼吸运动管理技术等辅助治疗来减小呼吸运动造成的影响。本文总结了这几种技术的研究现状,并基于各技术存在的问题对未来的研究方向进行了展望。

Stereotactic body radiotherapy,a hypofractionated radiation therapy method with fewer fractions and a large single radiation dose,is the preferred method for treating patients with early-stage non-small cell lung cancer who are clinically unsuitable for or refuse surgery.Accuracy and repeatability requirements of the target position are,therefore,necessary.In view of this,adjuvant treatments such as image-guided and respiratory motion management technology and immobilization devices are used clinically to reduce the impact of respiratory motion.This paper summarizes the research status of these approaches and proposes future directions based on the problems existing in each technology.