慢性肝病合并戊型肝炎病毒感染的研究现状及对策

Research status and countermeasures of chronic liver disease complicated with hepatitis E virus infection

戊型肝炎病毒(HEV)是全球急性散发性病毒性肝炎的重要病因之一。研究表明HEV感染是导致慢性肝病患者病情恶化的重要诱因,显著增加慢性肝炎或肝硬化患者肝衰竭的风险及病死率。文章对慢性肝病合并HEV感染的流行病学、临床研究、机制研究以及临床对策进行综述。

Hepatitis E virus(HEV)is one of the important causes of acute sporadic viral hepatitis worldwide.Studies have shown that HEV infection is an important cause of disease deterioration in patients with chronic liver disease,and significantly increases the risk of liver failure and mortality in patients with chronic hepatitis or cirrhosis.This article aims to review the epidemiology,clinical studies,mechanism studies and clinical countermeasures of chronic liver disease complicated with hepatitis E virus infection.