长春市儿童急性下呼吸道感染的病原学分析

Etiology of Acute Lower Respiratory tract infection in children in Changchun

目的了解长春市儿童下呼吸感染病原学特征及其分布规律,为本地区儿童下呼吸道感染的临床治疗提供的参考依据。方法采用Realtime PCR方法对2018年12月至2019年11月份采集的73份儿童支气管肺泡灌洗液标本进行28种病原及亚型检测。结果儿童下呼吸道感染中非典型病原体以支原体为主,病毒病原以呼吸道腺病毒、EB病毒、副流感病毒以主,细菌病原感染以流感嗜血杆菌为主。不同的病原体表现不同的流行期。结论通过对长春市儿童下呼吸道感染进行多病原检测,掌握病原流行特点,不同季节的呼吸道病原谱不一致。

Objective To understand the etiology and distribution of children's lower respiratory tract infection in Changchun,and to provide reference for clinical treatment of children's lower respiratory tract infection.Methods Real time PCR was used to detect 28 pathogens and subtypes in 73 samples of children's Bronchoalveolar lavage collected from December 2018 to November 2019.Results In children with lower respiratory tract infection,Mycoplasma was the main atypical pathogen.Respiratory Adenovirus,Epstein-Barr virus and Parainfluenza virus were the main pathogens,and bacterial pathogens were mainly Haemophilus influenzae.Different pathogens show different periods of prevalence.Conclusionn Through the detection of multiple pathogens in children with lower respiratory tract infection in Changchun,the epidemic characteristics of the pathogens are known,and the pathogen spectrum is different in different seasons.