摘要
开发既能抑制细菌感染又能主动促愈合的敷料,对修复创面以及医疗技术的发展具有十分重要的意义。电刺激在创面愈合过程中具有止血、抗菌、抗炎、引导细胞迁移、促再上皮化以及促细胞增殖等多重作用。金属微电池可在无须外接电源的情况下,提供稳定的电刺激能量来源。因此金属微电池与医用敷料的一体化集成,为电刺激在创面修复领域的无线应用带来了新的机遇。该文在介绍电刺激对创面愈合作用机制的基础上,从制备、抗菌、促愈合等角度综述了金属微电池敷料在创面修复中的研究进展,并详细介绍了当前不同类型金属微电池敷料的发展现状、面临的挑战以及未来的发展趋势。
To develop the dressings that can both inhibit bacterial infection and actively promote healing is of great importance for wound repair and the development of medical technology.Electrical stimulation has multiple roles in wound healing,including hemostasis,antibacterial,anti-inflammatory,guidance of cell migration,promotion of re-epithelialization,and proliferation of cells.Metal micro-battery can provide a stable source of electrical stimulation energy without an external power source.Thus,the integration of metal micro-battery with medical dressings opens up new opportunities for the wireless application of electrical stimulation in wound repair.In this review,the mechanism of the effect of electrical stimulation on wound healing is systematically presented,then recent advances in metal micro-battery dressings,including preparation methods,antibacterial performance,and healing properties are mainly introduced,and the current challenges and prospects of metal micro-battery dressings are also provided.
作者
陈锦苗
陈萌
任晓川
陈为超
王娜
李纪伟
Chen Jinmiao;Chen Meng;Ren Xiaochuan;Chen Weichao;Wang Na;Li Jiwei(College of Textile&Clothing,Qingdao University,Institute of Nonwovens and Industrial Textile Innovation,Qingdao 266071,China)
出处
《中华烧伤与创面修复杂志》
CAS
CSCD
北大核心
2023年第6期596-600,共5页
Chinese Journal of Burns And Wounds
基金
国家自然科学基金青年科学基金项目(52203060)
山东省高等学校青创科技支持计划创新团队(2022KJ152)
中国博士后科学基金面上项目(2022M711735)
青岛市市南区科技计划项目(2022-3-009-SW)。
关键词
生物敷料
电刺激疗法
伤口愈合
金属微电池
Biological dressings
Electric stimulation therapy
Wound healing
Metal micro-battery
