升阳益胃汤加减治疗消化心身疾病脾虚湿困证56例

Clinical effect of modified Shengyang Yiwei decoction in treatment of digestive psychosomatic diseases with syndrome of dampness stagnancy due to spleen deficiency:An analysis of 56 cases

目的:探讨升阳益胃汤加减治疗消化心身疾病脾虚湿困证的临床疗效。方法:根据不同病种将110例消化心身疾病脾虚湿困证患者随机分为治疗组和对照组,治疗组(56例)采用升阳益胃汤加减治疗,对照组(54例)采用氟哌噻吨美利曲辛片治疗,2组患者若伴有器质性疾病或症状较重者则予以对症治疗。比较2组中医证候疗效、中医证候评分及躯体症状群积分。结果:中医证候疗效总有效率治疗组为87.50%(49/56),对照组为68.52%(37/54),差异有统计学意义(P<0.01)。2组中医主症(反酸烧心、胃胀)评分、中医次症评分、躯体症状群积分治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05);治疗组腹痛、口疮评分及对照组腹痛评分治疗前后比较,差异均有统计学意义(P<0.05)。结论:升阳益胃汤加减治疗消化心身疾病脾虚湿困证疗效较好,能有效改善患者的临床症状,缓解患者焦虑、抑郁情绪。

Objective:To investigate the clinical effect of modified Shengyang Yiwei decoction in the treatment of digestive psychosomatic diseases with syndrome of dampness stagnancy due to spleen deficiency.Methods:According to the type of disease,110 patients with digestive psychosomatic diseases with syndrome of dampness stagnancy due to spleen deficiency were randomly divided into treatment group with 56 patients(treated with modified Shengyang Yiwei decoction)and control group with 54 patients(treated with flupentixol and melitracen tablets),they were treated by symptomatic therapy if those two groups of patients accompanied by organic disease or severe symptoms.The two groups were compared in terms of the treatment outcome of traditional Chinese medicine(TCM)syndrome,TCM syndrome score,and somatic symptom score.Results:There was a significant difference in overall response rate between the treat-ment group and the control group[87.50%(49/56)vs 68.52%(37/54),P<0.01].After treatment,both groups had significant changes in the scores of major TCM symptoms(acid reflux,heartburn,and stomach distension),the scores of minor TCM symptoms,and somatic symptom score,and there were significant differences in these scores between the two groups after treatment(P<0.05).The treatment group had significant changes in the scores of abdominal pain and aphtha after treatment,while the control group had a significant change in the score of abdominal pain after treatment(P<0.05).Conclusion:Modified Shengyang Yiwei decoction has a good clinical effect in the treatment of digestive psy-chosomatic diseases with syndrome of dampness stagnancy due to spleen deficiency and can effectively improve clinical symptoms and alleviate anxiety and depression emotions.