豫北地区中青年原发性高血压患者的临床特点分析

Clinical Characteristics Analysis of Young And Middle-aged Patients with Primary Hypertension in Northern Henan

目的分析豫北地区青中年原发性高血压患者临床特点,早期检测动脉硬化状况的深入认识及早发现血管的病变,以便进行早期干预。方法研究对象来自2018年1月-2020年7月在安阳市第三人民医院就诊的300例高血压患者及健康体检人群,分为青年高血压组和健康对照组,即青中年高血压组120例和健康对照组180例。比较两组患者不良生活习惯及嗜好、血压控制情况、动脉粥样硬化等差异。结果青年高血压组患者熬夜比例、BMI值高于对照组,差异有统计学意义(P<0.05);青中年高血压组IMT值大于健康对照组,差异有统计学意义(P>0.05);青中年高血压组斑块发生率大于健康对照组,差异有统计学意义(P>0.05);血管内皮功能比较:两组患者D0、D1比较差异无统计学意义(P>0.05);两组患者FMD比较,差异有统计学意义(P<0.05)。结论中青年高血压患者多生活不规律,早期即存在内皮功能障碍及IMT增厚。

Objective To analyze clinical characteristics of young and middle-aged patients with primary hypertension in northern Henan,to have deeper understanding of early detection of arteriosclerosis and vascular lesions for early intervention.Methods The paper chose 300 hypertensive patients and healthy individuals in Anyang City The Third People's Hospital from January 2018 to July 2020 as research objects,and divided them into youth hypertension group and healthy control group,with 120 cases in young and middle-aged hypertension group and 180 cases in healthy control group.Difference of bad living habits and hobbies,blood pressure control and atherosclerosis between two groups was compared.Results Proportion of staying up late and BMI values of young hypertensive patients were higher than control group,with statistical difference(P<0.05).IMT value of young and middle-aged hypertensive group was higher than healthy control group,with statistically significant difference(P>0.05).Incidence of plaques in young and middle-aged hypertensive group was higher than healthy control group,with statistically significant difference(P>0.05).Comparison of vascular endothelial function:there was no statistically significant difference in D0 and D1 between two groups,(P>0.05),with statistically significant difference in FMD between two groups,(P<0.05).Conclusion Most young and middle-aged hypertensive patients have irregular lifestyles,with early endothelial dysfunction and IMT thickening.