摘要
一直以来脑白质的作用常被忽视,随着神经影像技术的发展,脑白质的作用日益得到重视。围术期认知功能障碍一直以来是麻醉领域研究的热点问题,近年来有研究表明脑白质可能与全麻药物对认知功能影响机制相关。本文叙述了脑白质与认知的关系,并从临床和实验研究两个方面总结白质与全麻对认知影响的关系研究进展,以期为对该机制进一步研究提供新思路。
The role of white matter of brain has always been neglected by scholars.With the development of neuroimaging technology,the role of white matter has attracted increasing attention.Perioperative neurocognitive disorders have been a hot issue in the research on anesthesia,and recent studies have suggested that white matter may be involved in the effects of general anesthetics on cognitive function.This paper reviews the progress in the relationship between white matter,general anesthesia,and cognitive function from clinical practice and research,aiming to provide new ideas for the research on the mechanism.
作者
谢云帆
田毅
XIE Yunfan;TIAN Yi(Department of Anesthesiology,Central South University Xiangya School of Medicine Affiliated Haikou Hospital,Haikou 570208,China)
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2023年第3期479-483,共5页
Acta Academiae Medicinae Sinicae
基金
国家自然科学基金(81660195)
海南省自然科学基金高层次人才项目(821RC724)
海南省医药卫生项目(20A200157)。
关键词
脑白质
全身麻醉
认知功能
机制
white matter
general anesthesia
cognitive function
mechanism
