100例儿童流感嗜血杆菌相关社区获得性肺炎的回顾性分析

Retrospective Analysis of Community Acquired Pneumonia Associated with Haemophilus Influenzae in Children over 5 Years Old

目的回顾性分析某医院5岁以上儿童流感嗜血杆菌相关社区获得性肺炎检出率及其耐药性。方法研究选取三明市第二医院2017年12月—2022年12月临床收治5岁以上流感嗜血杆菌相关社区获得性肺炎患儿100例为本次研究对象,对100例患儿流感嗜血杆菌相关社区获得性肺炎不同性别、不同季节等占比以及流感嗜血杆菌相关社区获得性肺炎耐药性情况进行探究分析。结果100例患儿中,男性占比52.00%,女性占比48.00%,组间差异无统计学意义(P>0.05),在不同季节占比中,春季占比最高,为31.00%,其组间差异有统计学意义(X^(2)=4.367;P<0.05);不同年龄段中,6~8岁患儿占比最高,为41.00%,组间差异有统计学意义(X^(2)=6.963;P<0.05);100株流感嗜血杆菌耐药性分析中,对复方磺胺甲噁唑的耐药率最高,为81.00%,耐药率排名第二为氨苄西林/舒巴坦,第三为氨苄西林,耐药率分别为79.00%、76.00%;流感嗜血杆菌对美罗培南耐药率最低,为2.00%。结论流感嗜血杆菌相关社区获得性肺炎春季占比最高,且6~8岁患儿占比高,临床在对流感嗜血杆菌相关社区获得性肺炎患儿进行用药治疗的过程中,应针对患儿的实际情况用药,合理分配临床医疗资源。

Objective To retrospectively analyze the detection rate and drug resistance of community acquired pneumonia related to Haemophilus influenzae in children aged 5 and above.Methods The study selected 100 children with community-acquired pneumonia over 5 years old from December 2017 to December 2022 as the subjects of this study.The Percentage of Haemophilus influenzae related community acquired pneumonia in 100 children of different genders and seasons,as well as the drug resistance of Haemophilus influenzae related community acquired pneumonia were investigated and analyzed.Results Among the 100 patients,the male Percentage was 52.00%,while the female Percentage was 48.00%.There was no statistically significant difference between the groups(P>0.05).Among the Percentage in different seasons,the spring Percentage was the highest(31.00%),with a statistically significant difference between the groups(X^(2)=4.367;P<0.05);Among different age groups,the Percentage of children aged 6 to 8 years was the highest(41.00%),and the difference between groups was statistically significant(X^(2)=6.963;P<0.05).In the drug resistance analysis of 100 strains of Haemophilus influenzae,the drug resistance rate to compound sulfamethoxazole was the highest(81.00%),followed by ampicillin/sulbactam and ampicillin(79.00% and 76.00% respectively);The drug resistance rate of Haemophilus influenzae to meropenem was the lowest(2.00%).Conclusion The Percentage of Haemophilus influenzae related community-acquired pneu⁃monia is the highest in spring,and the prevalence rate of children aged 6 to 8 years is high.In the process of clinical medication for children with Haemophilus influenzae related community-acquired pneumonia,drugs should be used according to the actual situation of children,and clinical medical resources should be reasonably allocated.