摘要
生命体的氧化应激参与各种疾病的发生发展进程,而氧化应激的发生与血管紧张素转化酶(ACE)有密切联系。研究ACE结构特征与疾病关联机制,有助于阐明相关疾病的发病机制及研发靶向药物。该文综述了ACE与相关疾病的关联机制。
Oxidative stress is involved in the development of various diseases,which is closely related to angiotensinconverting enzyme(ACE).The structural features and correlative mechanism of ACE and associated diseases will be helpful to understand the pathogenesis of these disorders and develop targeted drugs.This article reviews the correlative mechanism of ACE and associated diseases.
作者
黄妙恩
罗辉
吕应年
HUANG Miao-en;LUO Hui;LV Ying-nian(Guangdong Key Laboratory for Research and Development of Natural Drugs,Zhanjiang 524023,China;Zhanjiang Institute of Marine Medicine,Zhanjiang 524023,China;Guangdong Laboratory of Southern Marine Science and Engineering,Zhanjiang 524023,China)
出处
《广东医科大学学报》
2023年第3期335-339,共5页
Journal of Guangdong Medical University
基金
湛江市科技计划项目(2020A04005)
南方海洋科学与工程广东省实验室(湛江)重点项目(ZJW-2019-007)。