摘要
The sensory system develops earlier than the systems responsible for higher brain functions such as language and cognition[1].Moreover,sensory experiences in early life are critical for the development of the brain.However,how sensory experiences shape brain development is an important yet unresolved question in neuroscience.Previous work has demonstrated that deprivation of sensory inputs in the early developmental stage causes synaptic dysfunction in the sensory cortex.Interestingly,it has been reported that oxytocin can restore the deficits caused by somatosensory deprivation in neonatal mice,suggesting that oxytocin may play a key role in sensory-mediated synaptogenesis[2].Vision is one of the most important sensory inputs during early development in mammalians including humans[1],but the neural mechanism underlying vision-mediated brain development is still largely unknown.
基金
supported by grants from the National Natural Science Foundation of China(32125018 and 32071005)
the Fundamental Research Funds for the Central Universities,the MOE Frontiers Science Center for Brain Science&Brain-Machine Integration of Zhejiang University,and Innovative Research Team of High-level Local Universities in Shanghai(SHSMU-ZDCX20211102).
