莲黄酮类化合物鉴定、功能与应用的研究进展

Advances in the identification,function,and application of flavonoids in Nelumbo

莲(Nelumbo)是一种重要的水生经济作物,富含黄酮、生物碱、多糖等生物活性物质,可药食两用。目前在莲中已经鉴定出超过百种的黄酮类化合物,包括芦丁、槲皮素、金丝桃苷等,这些物质具有抑菌抗炎、降脂减肥、抗氧化等多种药用功效。本文介绍了莲黄酮类化合物的种类,以及包括大孔树脂色谱法和高效液相色谱-质谱联用法在内的提取与鉴定方法,并对莲黄酮类化合物的功能活性、功能产品开发及其在疾病治疗中的最新应用进行了系统总结,以期为莲黄酮类化合物的科学研究和综合利用提供参考。

Lotus(Nelumbo)is an economically important aquatic crop and contains abundant bioactive compounds,such as flavonoids,alkaloids,and polysaccharides.More than 100 flavonoids have been identified in lotus,including rutin,quercetin,and chrysin,which exhibit various antibacterial,anti-obesity,and antioxidant medicinal properties.In this review,we introduce the types of flavonoids in lotus and various effective extraction and identification methods,including microporous resin chromatography(MPRC)and high-performance liquid chromatography tandem mass spectrometry(HPLC-MS/MS).Moreover,the functional activities of flavonoids in lotus and their latest applications,including disease treatment and functional product development,are further summarized.This review provides a reference for future research and the comprehensive utilization of lotus flavonoids.