十二烷基氯化吡啶合成工艺的热危险性研究

Study on the Thermal Hazard of the Synthesis Process of Dodecyl Pyridine Chloride

利用全自动反应量热仪(RC1mx)、差示扫描量热仪(DSC)和绝热加速量热仪(ARC)检测十二烷基氯化吡啶合成反应的反应热、最大反应温度及热稳定性,依据绝热温升(ΔT_(ad))、最大反应速率到达时间为24 h的温度(T_(D24))和失控体系可能达到的最高温度(MTSR)等温度参数对工艺危险性进行评估。结果显示,ΔT_(ad)为276.2 K,T_(D24)为290℃,MTSR为165.6℃。经过研究反应温度和吡啶滴加时间,确认了145℃是合理的反应温度。如果缩短吡啶滴加时间会导致物料累积,影响反应转化率,增加危险性。

The reaction heat,specific heat capacity,and thermal stability of the synthesis reaction of dodecylpyridinium chloride were measured using a fully automated reaction calorimeter(RC1mx),differential scanning calorimeter(DSC),and accelerating rate calorimeter(ARC).The process risk is evaluated based on temperature parameters such as adiabatic temperature rise(ΔT_(ad)),a temperature with a maximum reaction rate arrival time of 24 hours(T_(D24)),and the maximum temperature that may be reached by the runaway system(MTSR).The results showed that the ΔT_(ad) was 276.2 K,T_(D24) was 290℃,and MTSR was 165.6℃.After examining the reaction temperature and pyridine titration time,it was determined that 145℃was an acceptable reaction temperature.After studying the reaction temperature and pyridine dropping time,it is confirmed that 145℃is a reasonable reaction temperature.If the dropping time of pyridine was shortened,the reaction material would accumulate,which would affect the reaction conversion rate and increase the risk.