单独TI-RADS、超声弹性成像及二者联合对甲状腺良恶性结节的鉴别价值

Analysis of the differential value of TI-RADS alone,ultrasound elastography,and their combination in the diagnosis of benign and malignant thyroid nodules

目的探讨甲状腺影像报告与数据系统(thyroid imaging reporting and data system,TI-RADS)与超声弹性成像对甲状腺良恶性结节的鉴别价值。方法选取2018年6月至2022年6月于陕西省中医医院接受灰阶超声和超声弹性成像检查甲状腺结节患者70例作为研究对象。绘制受试者工作特征(receiver operating characteristic,ROC)曲线,计算曲线下面积(AUC)、敏感度、特异度、阴性预测值和阳性预测值,分析TI-RADS和超声弹性成像技术对甲状腺良恶性结节的鉴别价值。以病理学检查结果为金标准,分析TI-RADS和超声弹性成像技术鉴别甲状腺良恶性结节准确率。结果70例患者共129个实性结节,病理学检查结果显示良性结节89个,恶性结节40个。以病理学检查结果为金标准,TI-RADS联合超声弹性成像诊断甲状腺良恶性结节符合率显著高于单独TI-RADS检测(P<0.01)。超声弹性成像鉴别甲状腺良恶性结节敏感度显著高于单独TI-RADS检测(P<0.01)。TI-RADS联合超声弹性成像诊断甲状腺良恶性结节敏感度、特异度、AUC均显著高于单一方法(P<0.05)。结论TI-RADS联合超声弹性成像鉴别诊断甲状腺良恶性结节的敏感度和准确度较高,优于单一方法,可为患者治疗方案的制定提供可靠依据,值得临床推广。

Objective Explore the differential value of thyroid imaging reporting and data system(TI-RADS)and ultrasound elastography in the diagnosis of benign and malignant thyroid nodules.Methods 70 patients with thyroid nodules who underwent gray scale ultrasound and ultrasound elastography examinations at Shaanxi Provincial Traditional Chinese Medicine Hospital from June 2018 to June 2022 were selected as the research subjects.The receiver operating characteristic(ROC)curve was plotted,and the area under the curve(AUC),sensitivity,specificity,negative predictive value,and positive predictive value were calculated to analyze the differential value of TI-RADS and ultrasound elastography technology for benign and malignant thyroid nodules.Using pathological examination results as the gold standard,the accuracy of TI-RADS and ultrasound elastography in distinguishing benign and malignant thyroid nodules was analyzed.Results A total of 129 solid nodules were found in 70 patients,with pathological examination results showing 89 benign nodules and 40 malignant nodules.Based on the pathological examination results as the gold standard,the diagnostic accuracy of TI-RADS combined with ultrasound elastography for benign and malignant thyroid nodules was significantly higher than that of TI-RADS alone(P<0.01).The sensitivity of ultrasound elastography in distinguishing benign and malignant thyroid nodules was significantly higher than that of TI-RADS alone(P<0.01).The sensitivity,specificity,and AUC of TI-RADS combined with ultrasound elastography in the diagnosis of benign and malignant thyroid nodules were significantly higher than those of a single method(P<0.05).Conclusion The combination of TI-RADS and ultrasound elastography has a high sensitivity and accuracy in the differential diagnosis of benign and malignant thyroid nodules,which is superior to a single method.It can provide a reliable basis for the formulation of patient treatment plans and is worthy of clinical promotion.