腹腔镜结直肠癌根治术后并发下肢深静脉血栓的相关影响因素分析

Analysis of Related Factors of Lower Extremity Deep Venous Thrombosis After Laparoscopic Radical Resection of Colorectal Cancer

目的分析腹腔镜结直肠癌根治术后并发下肢深静脉血栓(DVT)的相关影响因素。方法选择115例结直肠癌患者,均行腹腔镜结直肠癌根治术治疗,依据患者是否发生DVT分为DVT组、无DVT组。统计患者术后并发DVT情况,分析患者术后并发DVT的相关影响因素。结果115例结直肠癌患者术后并发DVT有21例,DVT发生率为18.26%;DVT组伴有静脉血栓史、糖尿病史、高血压病史、围手术期感染占比高于无DVT组,年龄大于无DVT组,术后制动时间长于无DVT组,D-D、FIB、血浆黏度高于无DVT组,有统计学差异(P<0.05);Logistic回归分析显示,静脉血栓史、糖尿病史、高血压病史、围手术期感染、年龄、术后制动时间、D-D、FIB、血浆黏度是患者术后并发DVT的影响因素(P<0.05且OR≥1)。结论腹腔镜结直肠癌根治术后并发DVT的危险因素包括静脉血栓史、糖尿病史、高血压病史、围手术期感染、年龄、术后制动时间、D-D、FIB、血浆黏度等,临床上可结合上述危险因素,制定有效的DVT防治措施。

Objective To analyze the related factors of lower extremity deep venous thrombosis(DVT)after laparoscopic radical resection of colorectal cancer.Methods 115 patients with colorectal cancer were selected and treated with laparoscopic radical resection of colorectal cancer.According to whether the patients had DVT,they were divided into DVT group and no DVT group.The postoperative complications of DVT were counted,and the related influencing factors of postoperative complications of DVT were analyzed.Results There were 21 cases of postoperative DVT in 115 patients with colorectal cancer,and the incidence of DVT was 18.26%;Group DVT was associated with venous thrombosis history,diabetes history,hypertension history,and perioperative infection rate.It was higher than that in group DVT,older than DVT group.Postoperative braking time was longer than that without DVT group.D-D,FIB and plasma viscosity were higher than those without DVT group(P<0.05).Logistic regression analysis showed that venous thrombosis history,diabetes history,hypertension history,perioperative infection,age,postoperative immobilization time,D-D,FIB and plasma viscosity were the influencing factors of postoperative DVT(P<0.05 and OR>1).Conclusion The risk factors of DVT after laparoscopic colorectal cancer surgery include history of venous thrombosis,history of diabetes,history of hypertension,perioperative infection,age,postoperative immobilization time,D-D,FIB and plasma viscosity.Clinically,effective DVT prevention and treatment measures can be combined with these risk factors.