康复新液对中度慢性牙周炎患者的影响

Effect of Kangfuxin Liquid on patients with moderate chronic periodontitis

目的探讨康复新液对中度慢性牙周炎患者的影响。方法选取新疆医科大学第一附属医院2020年9月至2021年12月收治的80例中度慢性牙周炎患者,采用随机数字表法将其分为治疗A组(40例)和治疗B组(40例)。治疗A组采取龈下刮治和根面平整(SRP)及康复新液辅助治疗,治疗B组采取SRP及西帕依固龈液辅助治疗,两组均连续用药1个月。比较两组治疗前后的牙周指标、炎症因子指标和氧化应激指标变化。结果治疗后,两组菌斑指数、龈沟出血指数、探诊深度、临床附着丧失水平、肿瘤坏死因子-α、白细胞介素-6和丙二醛均低于治疗前,且治疗A组低于治疗B组,差异有统计学意义(P<0.05)。结论康复新液辅助SRP治疗中度慢性牙周炎能够改善患者的牙周指标,减轻牙周组织炎症反应和氧化应激反应,利于患者牙周组织恢复健康,效果优于西帕依固龈液。

Objective To investigate the effect of Kangfuxin Liquid on patients with moderate chronic periodontitis.Methods A total of 80 patients with moderate chronic periodontitis admitted to the First Affiliated Hospital of Xinjiang Medical University from September 2020 to December 2021 were selected and divided into treatment A group(40 cases)and treatment B group(40 cases)by random number table method.The treatment A group was treated with scaling and root planning(SRP)and Kangfuxin Liquid,and the treatment B group was treated with SRP and Xipayi Guyin Ye.Both groups were treated continuously for one month.The changes of periodontal indexes,inflammatory factors,and oxidative stress indexes were compared between the two groups before and after treatment.Results After treatment,the plaque index,sulcus bleeding index,probing depth,clinical attachment loss level,tumor necrosis factor-α,interleukin-6,and malondialdehyde in the two groups were lower than those before treatment,and those in the treatment A group were lower than those in the treatment B group,and the differences were statistically significant(P<0.05).Conclusion Kangfuxin Liquid combined with SRP in the treatment of moderate chronic periodontitis can improve the periodontal indexes of patients,reduce the inflammatory response and oxidative stress response of periodontal tissue,and promote the recovery of periodontal tissue.The effect is better than Xipayi Guyin Ye.